als

ALS-1 is an acid-Liable surfactant.This compound is unstable in powder form and other related salt forms are recommended.

ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.

ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM. ALS-8112 exhibits antiviral activity and inhibits the RNA polymerase activity of the RSV L-P protein complex through RNA chain termination. virus infections.

ALS22335 is an antiviral agent.

Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase.

Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.

Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.

Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]

AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.

Lumicitabine (ALS-008176) is an inhibitor of RSV polymerase.

Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.

Imazamox ((±)-Imazamox) is a systemic herbicide with high selectivity, high activity, safety and broadspectrum activity. Imazamox inhibits the production of acetolactate synthase (ALS) in plants, which would then inhibit plant growth and ultimately lead to plant death.

Palsucibep pegol is an engineered protein that specifically binds to human lipocalin-2. It also targets hepcidin [1].

Walsuralactam A in the formula I, which is used as an active ingredient, and is used for treating and preventing the tumour.

Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks. Berotralstat functions by inhibiting the enzymatic activity of plasma kallikrein, which is responsible for the release of bradykinin. This blocking mechanism targets the major biologic peptide involved in the promotion of swelling and pain associated with HAE attacks[1][2].

(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boasting a K i value of 26 μM compared to the S form.

4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.

amino acid that occurs naturally in the CNS

Valsartan D9 is a deuterium-labeled valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure.

rac Salsolinol, Hydrobromide is a useful organic compound for research related to life sciences. The catalog number is T124585 and the CAS number is 59709-57-8.

Przewalskinic acid A is a rare, water-soluble, and highly biologically active ingredient found, thus far, only in the Salvia przewalskii Maxim herb.

Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).

Walsuronoid B shows weak antimalarial activity.

Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan. It is a degradation product formed under acidic conditions.

Alstonidine acetate is a biochemical.

Alstolenine is a natural product of Alstonia, Apocynaceae. The catalog number is TN3398 and the CAS number is 85769-33-1. Alstolenine can be used as a reference standard.

Venalstonine is a useful organic compound for research related to life sciences and the catalog number is T131406.

Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.

Alseroxylon can be used to treat hypertension.

Talsaclidine is an agonist of muscarinic with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes.

Alsactide, an adrenocorticotropic hormone (ACTH) agonist and a heptadecapeptide analogue, is utilized in the study of the central nervous system [1].

Alstonidine acetate trihydrate is a biochemical.

Feniralstat is a pyrazole derivative, a potent inhibitor of kallikrein, which inhibits human plasma kinase (pKal) (IC50: 6.7 nM).Feniralstat does not inhibit human KLK1, human FXIa and human factor Xlla (IC50 >40 μM).

Uralsaponin D displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L, it could significantly increase the cytotoxic activity after hydrolysis.

Pralsetinib is a selective and next-generation RET inhibitor (IC50: 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T, and CCDC6-RET fusion). BLU-667 is an effective and selective inhibitor of RET mutations, fusions, and predicted resistant mutants.

Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE.

Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec

Alstonidine is a biochemical.

Isosalsolidine is a useful organic compound for research related to life sciences and the catalog number is T131573.

Valsartan benzyl ester is a intermediate of Valsartan.

Alstonic acid A is a natural product of Alstonia, Apocynaceae. The catalog number is TN3399 and the CAS number is 1159579-44-8. Alstonic acid A can be used as a reference standard.

(+/-)-Salsolinol hydrochloride is a full Gi protein agonist of the μ-opioid receptor (μOR).

rac-Valsartan-d9 is a deuterated compound of rac-Valsartan. rac-Valsartan has a CAS number of 137862-53-4. Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.

Alsterpaullone, 2-Cyanoethyl is a selective dual inhibitor of Cdk1/cyclin B and GSK-3β.

Alsevalimab is a human monoclonal antibody targeting B7-H4 [1].

Carnegine (Pectenine, N-Methylsalsolidine) is a useful organic compound for research related to life sciences and the catalog number is T131396.

Alstoyunine E shows selective inhibition of Cox-2 (>75%).

Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug. High dose Balsalazide sodium hydrate(3.0 g twice daily) was superior in maintaining remission in patients with ulcerative colitis compared with a low dose (1.5 g twice daily) or a standard dose of mesalazine (0.5 g three times daily). All three treatments were safe and well tolerated [1]. Balsalazide sodium hydrate is approved for the treatment of mild-to-moderate active UC. It is efficacious for the induction of remission in mild to moderate UC and has a favorable safety profile, with the added advantages of greater efficacy of remission induction and rapidity of onset [2].

Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1] .

Uralsaponin C shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L.