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By Target- Apoptosis
- PD-1/PD-L1(2)
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Search Result
Results for "
bms 202
" in TargetMol Product Catalog- Inhibitors & Agonists4
- PROTAC Products1
BMS-202
Cited
PD1-PDL1 inhibitor 2,PD-1 PD-L1 inhibitor 2
T31461675203-84-5
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) PD-Ll (Programmed death-ligand 1) protein protein interaction.
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CitedN-deacetylated BMS-202
T121432310135-18-1
N-deacetylated BMS-202 is the deacetylated form of BMS-202.
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BMS202 hydrochloride (1675203-84-5(free base))
PD-1 PD-L1 inhibitor 2 hydrochloride
T46962089334-95-0
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
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E3 ligase Ligand PG
T8865814149-34-9
E3 Ligase Ligand PG serves as an E3 ligase ligand capable of recruiting the CRBN protein. It demonstrates strong binding affinity with CRBN, exhibiting an IC50 of 2.191 μM. Furthermore, E3 Ligase Ligand PG can be linked via a linker to BMS-202 to form PROTAC, PROTACPD-L1degrader-1.
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