cinnamic acid

Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.

3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) is a plant-derived compound first extracted from roots of Asparagus officinalis and further characterized as an allelochemical.

trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.

4-(Dimethylamino)cinnamic acid (DMACA) could be as charge transfer (ICT) probe.

trans-4-(Trifluoromethyl)cinnamic acid is a photosensitizing compound. It is used as a reagent in the synthesis of various compounds, such as heterocyclic compounds and pharmaceuticals. It has also been used as a catalyst for organic reactions such as the Heck reaction and the Suzuki-Miyaura reaction. It is also used as a fluorescent probe in biological studies to detect and monitor various biomolecules.

Sodium cinnamate, a naturally occurring low-toxicity aromatic fatty acid with oral activity, exhibits neuroprotective and anti-inflammatory properties.

3,5-Dibromo-4-[3-(dimethylamino)propoxy]cinnamic acid is a useful organic compound for research related to life sciences and the catalog number is T126018.

Benzyl cinnamate (Benzylcinnamoate) is a natural product isolated from various plant species,with anti-inflammatory activity.

(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural compound derived from the roots and rhizomes of Notopterygium incisum.

p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.

p-Coumaric acid (para-Coumaric Acid) is the abundant isomer of cinnamic acid, with antitumor and anti-mutagenic activities.

1. trans-Cinnamaldehyde (Phenylacrolein) exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. 2. Cinnamic aldehyde induces apoptosis of CML cells in vitro, down-regulation of the expression and function of BCR-ABL may be one of its most important anti-leukemia mechanisms. 3. Cinnamic aldehyde and cinnamic acid are cardioprotective in a rat model of ischemic myocardial injury, the mechanism is related to anti-oxidative and anti-inflammatory properties.

Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73A P450 subpopulation.

4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents.

4-Chloro-α-cyanocinnamic acid (Cl-CCA), a phenylpropanoid derivative of cinnamic acid synthesized from phenylalanine by plants, exhibits a propensity for co-crystallization with a range of biomolecules, including peptides and nucleic acids.

Cinnamoylglycine, a glycine conjugate of cinnamic acid and a urinary metabolite in humans, is used as a potential urinary biomarker.