Search Result

Search Results for " keratinocyte "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1328	TB500		Others
	TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.		Others
T10687	Casein Kinase II Inhibitor IV		Casein Kinase
	Casein Kinase II Inhibitor IV is an inducer of epidermal keratinocyte differentiation.		Casein Kinase
T20158	Phenformin	Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps	Apoptosis
	Phenformin (BRN 1977317) is a biguanide compound with anticancer and anti-glycemic activity, inhibits skin tumor growth and promotes keratinocyte differentiation and apoptosis.		Apoptosis
T6696	Tazarotene	Tazorac,AGN 190168,Zorac	Retinoid Receptor , Autophagy
	Tazarotene (Zorac) is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiati...		Retinoid Receptor , Autophagy
T27710	K6PC-5	K6PC5,K6PC 5	S1P Receptor
	K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels. With its potential applications in skin diseases associated ...		S1P Receptor
TP2308	TB500 acetate(885340-08-9 free base)	Frag17-23 Acetate,TB500 Acetate	Others
	TB500 acetate(885340-08-9 free base) (Frag17-23 Acetate) is a synthetic version of an active region of thymosin β4. It promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, col...		Others
TP2497	Myristoyl Tetrapeptide-12 Acetate	Myristoyl Tetrapeptide-12 Acetate(959610-24-3 Free base)	Others
	Myristoyl Tetrapeptide-12 Acetate (Myristoyl Tetrapeptide-12 Acetate (959610-24-3 Free base)) , the reaction product of myristic acid and Tetrapeptide-12, is a peptide stimulating hair and eyelash growth and enhancing th...		Others
T26958	CAY10583	CAY 10583,CAY-10583
	CAY10583 is an agonist of leukotriene B4 receptor type 2 (BLT2). CAY10583 directly promotes keratinocyte migration and indirectly enhances fibroblast proliferation by increasing keratinocyte production of bFGF1 and TGF-β...
T30526	BMS-480404	BMS 480404,BMS480404,UNII-T78485CEYD
	BMS-480404 is an effective small molecule inhibitor, which can bind to human keratinocyte fatty acid-binding protein.
T62055	NVS-BET-1
	NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.
T81330	Q-Peptide
	Q-Peptide, an angiopoietin-1 derived peptide (QHREDGS), enhances keratinocyte migration, thereby facilitating wound healing in a diabetic mouse model, and accelerates wound closure [1].
T35524	(1S)-Calcitriol
	(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3), a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), exerts potent actions through vitamin D receptor (VDR) activation, including the inhibition of keratin...
T37158	8(S)-HETE
	8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0...
T10687L	Casein Kinase II Inhibitor IV Hydrochloride	Casein Kinase II Inhibitor IV Hydrochloride (863598-09-8 free base)	Others
	Casein Kinase II Inhibitor IV Hydrochloride is a small-molecule inducer of epidermal keratinocyte differentiation that lead to novel therapeutic approaches for the treatment of skin hyperproliferative disorders.		Others
T61996	Antiproliferative agent-6
	Antiproliferative agent-6 (compound 8a) is a potent antitumor compound. Antiproliferative agent-6 shows antiproliferative activity. Antiproliferative agent-6 inhibits cancer cell lines HCT116, MCF-7, H460 and non-tumor a...
T37547	Trans-Urocanic Acid
	trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes ...
T36531	PAR2 (1-6) (mouse, rat)	PAR2 (1-6) (mouse, rat)
	PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 3...
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...
T35671	Salazinic Acid
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30...

Compounds

Casein Kinase II Inhibitor IV

T10687

Synonym:

Target: Casein Kinase

Phenformin

T20158

Synonym: Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps

Target: Apoptosis

Tazarotene

T6696

Synonym: Tazorac,AGN 190168,Zorac

Target: Retinoid Receptor, Autophagy

K6PC-5

T27710

Synonym: K6PC5,K6PC 5

Target: S1P Receptor

TB500 acetate(885340-08-9 free base)

TP2308

Synonym: Frag17-23 Acetate,TB500 Acetate

Target: Others

Myristoyl Tetrapeptide-12 Acetate

TP2497

Synonym: Myristoyl Tetrapeptide-12 Acetate(959610-24-3 Free base)

Target: Others

CAY10583

T26958

Synonym: CAY 10583,CAY-10583

Target:

BMS-480404

T30526

Synonym: BMS 480404,BMS480404,UNII-T78485CEYD

Casein Kinase II Inhibitor IV Hydrochloride

T10687L

Synonym: Casein Kinase II Inhibitor IV Hydrochloride (863598-09-8 free base)

Target: Others

Antiproliferative agent-6

PAR2 (1-6) (mouse, rat)

T36531

Synonym: PAR2 (1-6) (mouse, rat)

Target:

β-Defensin-2 (human) (trifluoroacetate salt)

Cat No.	Product Name	Targets
T3855	Tracheloside	Estrogen Receptor/ERR , Phosphorylase
	Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).	Estrogen Receptor/ERR , Phosphorylase
T37753	Aureusimine B	Cysteine Protease , Antibacterial
	Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide syntheta...	Cysteine Protease , Antibacterial

Natural Products

Tracheloside

T3855

Synonym:

Target: Estrogen Receptor/ERR, Phosphorylase

Aureusimine B

T37753

Synonym:

Target: Cysteine Protease, Antibacterial

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00400	FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00475	FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00397	FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00847	FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPJ-00073	FGF-7/KGF Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival a...
TMPK-00398	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)	Human	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPH-01866	PLET1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-02831	PLET1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-01865	PLET1 Protein, Human, Recombinant (His)	Human	E. coli
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-02830	PLET1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-02909	Sprr2a1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the f...
TMPH-02116	SPRR2B Protein, Human, Recombinant (His & Myc)	Human	Yeast
	Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the f...
TMPH-02879	REG3G Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of th...
TMPH-01536	ITGB4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG...
TMPH-00846	ABHD5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfert of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-ly...
TMPJ-01189	S100A15A Protein, Mouse, Recombinant	Mouse	E. coli
	Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor ma...
TMPJ-01073	FABP5 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl...
TMPJ-00924	Decorin Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPH-02834	PAI-1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...
TMPH-02833	PAI-1 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...
TMPY-02838	FGFBP3 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo...
TMPH-01826	Human Papilloma Virus type 11 (HPV 11) Protein E4 (His)	HPV 11	E. coli
	Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions. Induces host cell cycle arrest at the G2 ph...
TMPH-02594	MMP-13 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig...
TMPH-01839	Human Papilloma Virus type 6a (HPV 6a) Protein E4 (His & Myc)	HPV 6a	E. coli
	Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions. Induces host cell cycle arrest at the G2 ph...
TMPH-01831	Human Papilloma Virus type 16 (HPV 16) Protein E4 (His & Myc)	HPV 16	E. coli
	Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions. Induces host cell cycle arrest at the G2 ph...
TMPY-02174	FABP5 Protein, Human, Recombinant	Human	E. coli
	Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic...
TMPY-01824	Caspase-14 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses...
TMPH-01256	Dystonin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc...
TMPH-01257	Dystonin Protein, Human, Recombinant (His)	Human	Yeast
	Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc...
TMPH-01077	UGCG Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	Catalyzes at the cytosolic surface of the Golgi, the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway, the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/Gl...
TMPY-01953	CALML5 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is ...
TMPY-02103	FABP4 Protein, Human, Recombinant (29 Ala/Thr, His)	Human	E. coli
	Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalyc...
TMPY-01992	Kallikrein 8/KLK8 Protein, Human, Recombinant (His)	Human	HEK293
	Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Ka...
TMPY-01482	FABP4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalyc...