m34

M-34 is a bioactive chemical.

BPAM344 is a potent positive allosteric modulator (PAM) of the KAR subunits GluK1b, GluK2a, and GluK3a.

LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K .

M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.

YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).

BP-M345 (compound 5) serves as a powerful antiproliferative agent that selectively targets cancer cells while demonstrating minimal toxicity to non-tumor cells. It effectively inhibits cancer cell proliferation, achieving a GI 50 value between 0.17 to 0.45 μM [1].