malate dehydrogenase 1, nad

5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile is a compound used as a molecular structural unit and is considered to be an inhibitor of enzymes such as COX-2, 5-LOX, etc., and possesses a wide range of biochemical and physiological effects including antitumor activity, anti-inflammatory effects and antioxidant activity.

Aldehyde dehydrogenase NAD(P) (ALDH) is an enzyme that facilitates the conversion of aldehydes into their respective carboxylic acids while simultaneously reducing the cofactor NAD(P) to NAD(P)H, making it a key component in biochemical research. This enzyme plays a crucial role in mitigating aldehyde stress by being part of the body's array of enzymatic defenses [1].

Glucose 1-dehydrogenase, also known as glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase, is an enzyme that catalyzes the conversion of glucose and NAD(P) into NAD(P)H and gluconic acid, serving as a cofactor regeneration mechanism [1].

Glutamate dehydrogenase NAD(P) (GLDH) is a mitochondrial enzyme widely found in organisms that catalyzes the reversible oxidative deamination of glutamate to produce α-ketoglutarate (α-KG), which is used in the study of diseases caused by abnormalities in glutamate metabolism.

Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .