ndm-1 inhibitor-2

NDM-1 inhibitor-2 is an inhibitor of new delhi metallo-β-lactamase-1 (NDM-1).

IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.

YJ182 is an NDM-1 inhibitor with an IC50 of 0.23 μM, and additionally inhibits IMP-1, VIM-2, GIM-1, and MMP-2 with respective IC50 values of 0.25, 0.61, 0.49, and 6.92 μM. It is utilized in bacterial infection research [1].

MßL-IN-2I is a potent broad-spectrum metallo-β-lactamase (MβL) inhibitor which inhibits the MβLs NDM-1, VIM-2, ImiS, and L1.

Captopril (SQ 14225) hydrochloride is an antihypertensive agent that is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC 50 of 0.025 μM and has been widely used for research of hypertension and congestive heart failure. Captopril hydrochloride is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC 50 of 7.9 μM [1] [2] [3].

VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activity. IC50: 48 μM) and New Delhi Metal (NDM-1) (IC50: 231 μM).

EBL-3183, an indole-2-carboxylate, serves as a potent, reversible, non-covalent, and competitive inhibitor of metallo-β-lactamase (MBL), specifically targeting NDM-1 with a pIC50 of 7.7 [1].