OAB-14 is a Bexarotene derivative that improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the endosomal-autophagic-lysosomal(EAL) pathway in APP/PS1 transgenic mice [1] [2].

Dehydroabietinol (Pomiferin A) inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM).

Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histamine release from mast cells.

Koaburaside monomethyl ether is a natural product of Croton, Euphorbiaceae. The catalog number is TN4393 and the CAS number is 41514-64-1. Koaburaside monomethyl ether can be used as a reference standard.

Dehydroabietal, a natural product, is present in Pinus brutia var. eldarica, Cedrus atlantica, and various other organisms [1].

15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities.

12-Chlorodehydroabietic acid is a chlorinated resin acid.

(+)-Dehydroabietic acid is a natural compound isolated from Rosin acid.

7alpha,15-Dihydroxydehydroabietic acid may exhibit significant cytotoxic activity.

1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma triglyceride (TG) , and hepatic TG levels. 3. DAA derivatives displays anti-secretory and anti-pepsin effect in animal models.

16-Nor-7,15-dioxodehydroabietic acid is a useful organic compound for research related to life sciences and the catalog number is T126227.

Methyl 7α,15-dihydroxydehydroabietate is a natural product for research related to life sciences. The catalog number is TN5583 and the CAS number is 155205-65-5.

Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris . Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro.

Methyl 15-hydroxy-7-oxodehydroabietate is a useful organic compound for research related to life sciences and the catalog number is T124573.

7-Oxodehydroabietinol is a useful organic compound for research related to life sciences and the catalog number is T125012.

7-Oxodehydroabietic acid is a diterpene resin acid found in the roots of Pinus densiflora pine. It acts as a defensive compound against herbivorous insects by disrupting their endocrine system.

Methyl 7β,15-dihydroxydehydroabietate is a useful organic compound for research related to life sciences and the catalog number is T126441.

16-Nor-15-oxodehydroabietic acid is a natural product from Pinus massoniana.

Isoabsouline is a useful organic compound for research related to life sciences and the catalog number is T126378.

Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.

OABK hydrochloride is a small-molecule switch. It also can be used to control protein activity.

12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.

15-Hydroxy-7-oxodehydroabietic acid is a natural product of Pinus, Pinaceae. The catalog number is TN2638 and the CAS number is 95416-25-4. 15-Hydroxy-7-oxodehydroabietic acid can be used as a reference standard.

5,6-Dihydroabiraterone, a metabolic derivative of Abiraterone, is a potent and irreversible inhibitor of CYP17A1, exhibiting antiandrogen and antitumor activities, particularly effective against castration-resistant prostate cancer (CRPC) [1] [2].

NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activate voltage-gated Kv11.1 channels (hE

EP3 antagonist 3 (compound 2) is a highly effective and specific antagonist of the EP3 receptor. It displays significant oral bioavailability and exhibits a strong pKi value of 8.3. Furthermore, EP3 antagonist 3 possesses excellent pharmacokinetic characteristics, making it a suitable candidate for experimental investigations involving overactive bladder (OAB) research [1].

Propiverine is a potent antimuscarinic agent that effectively inhibits cellular calcium influx, leading to the reduction of muscle spasm. It exhibits neurotropic and musculotropic effects specifically on the smooth muscles of the urinary bladder. Propiverine proves valuable in research concerning overactive bladder (OAB) [1] [2].

Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).

TAK-259 is a novel, selective, and orally active α1D adrenergic receptor antagonist (α1D, Ki = 1.1 nM) that represents a promising new therapeutic agent for the treatment of symptoms of OAB. It has an anti-frequency effect and reduces the burden of the hu

Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).

ZD-0947, a K(ATP) channel activator, is used potentially for the treatment of overactive bladder (OAB).

Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo into its active metabolite 5-hydroxymethyl tolterodine, which binds and inhibits muscarinic receptors on the bladder detrusor muscle, thereby preventing bladder contractions or spasms caused by acetylcholine.

Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.

Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.

Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).

Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).