osc

1. Pseudoprotodioscin has moderate cytotoxicity.

L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.

Protodioscin (Furostanol I) is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.

Dioscin (Collettiside III) is a saponin with antitumor activities.

Cryptomoscatone D2 is a highly efficacious inhibitor of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.

7(8)-Dehydroschisandrol A (Compound 4a), a lignan extracted from Schizandra chinensis Baill, exhibits a mild inhibitory activity against stress-induced gastric ulcers [1].

Neoschaftoside has antioxidant activity.

Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE)

7(18)-Dehydroschisandro A (Compound 2), a lignan isolated from Schizandra chinensis Baill, exhibits inhibitory effects on stress-induced gastric ulcers [1].

Isoscoparin-2''-Beta-D-glucopyranoside shows prominent free radical scavenging activity in DPPH assay.

Isoscabertopin has anticancer activity.

Euphoscopin C, a diterpenoid isolated from Euphorbia helioscopia, significantly enhances the cytotoxic activity of natural killer (NK) cells against H1299-luci and A549-luci cells [1].

Boschnaloside is a natural product for research related to life sciences. The catalog number is TN6262 and the CAS number is 72963-55-4.

Isoscutellarein 8-O-β-D-glucuronide, a flavonoid antioxidant, can be isolated from the seeds of Theobroma grandiflorum [1] [2].

Isosclerone is a natural product.

Moscatin exhibits antiplatelet aggregation activity.

Dioscoreside E exhibits both cytotoxic and antifungal activities against a range of tumor cell lines.

Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, caspase-3, and mitochondrial cytochrome c.

Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.

Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is a potent serotonin A receptor agonist and candidate for amelioration of aggress

3-epi-Dihydroscandenolide is a natural product for research related to life sciences. The catalog number is TN5394 and the CAS number is 1137951-08-6.

Anhydroscandenolide is a natural product for research related to life sciences. The catalog number is TN5395 and the CAS number is 114742-71-1.

Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity

cis-Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells.

Meloscandonine is a natural product for research related to life sciences. The catalog number is TN4517 and the CAS number is 28645-27-4.

Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and treatment of obesity.

Geissoschizoline ((+)-Geissoschizoline), with IC50 values of 20.40 µM for human AChE and 10.21 µM for BChE, functions as a potent inhibitor and emerges as a promising multi-target prototype for research into preventing neurodegeneration and restoring neurotransmission. Additionally, it serves as a potent anti-inflammatory agent.

Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM.

2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard.

Apohyoscine is a natural product of Datura, Solanaceae. The catalog number is TN3434 and the CAS number is 535-26-2. Apohyoscine can be used as a reference standard.

L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. Hyoscyamine is a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.

Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.

Proscillaridin A is a natural product.It is a potent poison of topoisomerase I II activity with IC50 values of 30 nM and 100 nM, respectively.