pheniramine

Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived relaxing factor, nitric oxide.

Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of chlorpheniramine.

Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.

Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.

Brompheniramine ((±)-Brompheniramine) is a potent, orally active alkylamine class antihistamine and a selective antagonist of the histamine H1 receptor (Kd = 6.06 nM). It has applications in the research of allergic rhinitis and exhibits anticholinergic, antidepressant, and anesthetic properties. Brompheniramine blocks calcium channels, sodium channels, and hERG channels with IC50 values of 16.12 μM, 21.26 μM, and 0.90 μM, respectively [1] [2] [3] [4].

Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases.

Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.

Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the gastrointestinal tract, blood vessel

Dexbrompheniramine, an orally active H1 receptor antagonist (antihistamine), mitigates the impacts of the natural chemical histamine in the body. It is utilized in the study of hay fever and urticaria [1].