pyrrolizidine

1,2-Epoxy-1-hydroxymethylpyrrolizidine is a useful organic compound for research related to life sciences and the catalog number is T125765.

Monocrotaline (Crotaline) is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes is noted after oral magnesium treatment.

(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).

Supinine is a pyrrolizidine alkaloid.

Senkirkin is a pyrrolizidine alkaloid with hepatotoxicity.

Usaramine (Mucronatine) demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.

Rinderine N-oxide, a pyrrolizidine alkaloid, is present in R. graeca [1].

7-Acetylintermedine is a hepatotoxic botanical pyrrolizidine alkaloid.

Adonifoline is a hepatotoxic pyrrolizidine alkaloid.

Lasiocarpine is a pyrrolizidine alkaloid, it has acute cytotoxicity in human and hepatic cell lines.

Erucifoline, a pyrrolizidine alkaloid, is present in the aerial components of Senecio aquaticus.

Jacobine N-oxide is a pyrrolizidine alkaloid compound found in thrips-resistant Senecio hybrids.

Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.

Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduc

Seneciphylline N-oxide is a pyrrolizidine alkaloid obtained from Emilia sonchifolia and is the dehydrogenation product of Senecionine N-oxide.

Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.

Ligularine is a hepatotoxic otonecine-type pyrrolizidine alkaloid isolated from Ligularia hodgsonii, a Chinese traditional antitussive medicine.

Senecionine n-oxide is a major product of pyrrolizidine nucleic alkaloid biosynthesis in unusual root cultures of Trichoderma lucidum.Senecionine N-oxide (Senecionine oxide) has antitumor activity but induces hepatic sinusoidal obstruction syndrome.Senecionine n-oxide acts as a chelating tracer for N-oxide.

Desacetyldoronine is a hepatotoxic pyrrolizidine alkaloid.

Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury.

Senecionine acetate (O-Acetylsenecionine), a pyrrolizidine alkaloid, inhibits the sequestration of Ca2+ in both extramitochondrial and mitochondrial compartments, likely through the inactivation of free sulfhydryl groups [1].

Isatidine is a pyrrolizidine alkaoid.