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ra190

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  • Inhibitors & Agonists
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RA190
T138581617495-03-0
RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
  • $52
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RA375
T369022649154-57-2
RA375, an inhibitor of RPN13 (26S proteasome regulatory subunit), enhances UPR signaling, ROS production, and apoptosis. Demonstrating ten times the efficacy against cancer lines compared to RA190, RA375 owes its increased activity to nitro ring substituents and the inclusion of a chloroacetamide warhead.
  • $35
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