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Search Results for " rhythms "

Targets

11

Compounds

1

Natural Products

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T14004 1A-116 Rho
1A-116 is a specific inhibitor of Rac1 .
T9356 (E/Z)-GO289 Casein Kinase
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function...
T9608 KL201 Others
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1].
T32401 KL044 KL 044,KL-044 Others
KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP/PKA/CREB pathway.
T7219 Flecainide acetate Flecainide (acetate),R-818 Sodium Channel
Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).
T24083 Gallopamil, (-)- (-)-Methoxyverapamil,(S)-Gallopamil,(-)-Gallopamil,(-)-D 600
Gallopamil, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.
T24082 Gallopamil HCl, (-)- L-Gallopamil hydrochloride,(S)-Gallopamil hydrochloride,(-)-Gallopamil hydrochloride
Gallopamil HCl, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.
T63375 FT709
FT709 is a selective and potent inhibitor of USP9X (IC50: 82 nM). Among others, USP9X is associated with centrosome function, EGF receptor degradation, chromosome alignment during mitosis, chemosensitization and circadia...
T27430 GR 196429 GR-196429,GR 196,429,GR-196,429,GR196429,GR196,429
GR 196429, a melatonin receptor agonist, exhibits selectivity for the MT1 subtype. This compound not only promotes sleep and alters circadian rhythms but also stimulates melatonin release in mice.
T70812 PF-05236216 hydrochloride
PF-05236216 hydrochloride is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε) that modulates circadian rhythms in mice.
T80849 VU661
VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening.
Cat No. Product Name Synonyms Targets
T7938 Quinidine Parasite
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPH-02827 PPAR gamma Protein, Mouse, Recombinant (His) Mouse E. coli
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the tra...
TMPH-01900 DDX5 Protein, Human, Recombinant (His & Myc) Human E. coli
Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop r...
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