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Cat No. | Product Name | Synonyms | Targets |
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T14004 | 1A-116 | Rho | |
1A-116 is a specific inhibitor of Rac1 . | |||
T9356 | (E/Z)-GO289 | Casein Kinase | |
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function... | |||
T9608 | KL201 | Others | |
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1]. | |||
T32401 | KL044 | KL 044,KL-044 | Others |
KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP/PKA/CREB pathway. | |||
T7219 | Flecainide acetate | Flecainide (acetate),R-818 | Sodium Channel |
Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart). | |||
T24083 | Gallopamil, (-)- | (-)-Methoxyverapamil,(S)-Gallopamil,(-)-Gallopamil,(-)-D 600 | |
Gallopamil, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms. | |||
T24082 | Gallopamil HCl, (-)- | L-Gallopamil hydrochloride,(S)-Gallopamil hydrochloride,(-)-Gallopamil hydrochloride | |
Gallopamil HCl, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms. | |||
T63375 | FT709 | ||
FT709 is a selective and potent inhibitor of USP9X (IC50: 82 nM). Among others, USP9X is associated with centrosome function, EGF receptor degradation, chromosome alignment during mitosis, chemosensitization and circadia... | |||
T27430 | GR 196429 | GR-196429,GR 196,429,GR-196,429,GR196429,GR196,429 | |
GR 196429, a melatonin receptor agonist, exhibits selectivity for the MT1 subtype. This compound not only promotes sleep and alters circadian rhythms but also stimulates melatonin release in mice. | |||
T70812 | PF-05236216 hydrochloride | ||
PF-05236216 hydrochloride is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε) that modulates circadian rhythms in mice. | |||
T80849 | VU661 | ||
VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening. |
Cat No. | Product Name | Synonyms | Targets |
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T7938 | Quinidine | Parasite | |
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria. |
Cat No. | Product Name | Species | Expression System |
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TMPY-00286 | Neuropeptide Y Protein, Human, Recombinant (hFc) | Human | HEK293 |
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ... | |||
TMPH-02827 | PPAR gamma Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the tra... | |||
TMPH-01900 | DDX5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop r... |