Search Result

Search Results for " singlet "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TD0102	1,3-Diphenylisobenzofuran	DPBF	Others
	1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe. It possesses a highly specific reactivity towards singlet oxygen forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran c...		Others
T20548	Parabanic acid	NSC9789,NSC-9789,NSC 9789
	Parabanic acid is the oxidation product of uric acid by singlet oxygen.
T38970	Hematoporphyrin monomethyl ether
	Hematoporphyrin monomethyl ether (HMME), a second-generation porphyrin-related photosensitizer, is a highly selective and low-toxicity compound known for its singular form and high yield of singlet oxygen. It finds exten...
T35549	Elsinochrome A
	Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus ...
T74629	Benz-AP
	Benz-AP, a potent photosensitizer, generates singlet oxygen inversely related to Human carboxylesterase 2 (hCES2) activity, showcasing enhanced photocytotoxicity in cancer cells within low hCES2 environments. Moreover, u...
T34393	Rostaporfin	SnET2,tin etiopurpurin dichloride,tin ethyl etiopurpurin dichloride,Purlytin,Sn(IV) etiopurpurin
	Rostaporfin (also known as REM-001, tin ethyl etiopurpurin, Sn(IV) etiopurpurin, Purlytin, SnET2), is a synthetic purpurin with photosensitizing activity. Rostaporfin preferentially accumulates in tumor cells due to an i...
T36176	AMK (hydrochloride)
	AMK is an active metabolite of the neurohormone melatonin .1,2,3,4It is formed from melatoninviathe metabolic intermediate AFMK that is then deformylated by catalase or formamidase.5,6AMK scavenges singlet oxygenin vitro...
T77235	Methylene Violet 3RAX
	Methylene Violet 3RAX, a phenazine dye, is utilized for staining cell mitochondria and has the capability to alter DNA's molecular structure, disrupt DNA modules, and promote reactive singlet oxygen generation. It inhibi...

Compounds

1,3-Diphenylisobenzofuran

Synonym: NSC9789,NSC-9789,NSC 9789

Target:

Hematoporphyrin monomethyl ether

Synonym: SnET2,tin etiopurpurin dichloride,tin ethyl etiopurpurin dichloride,Purlytin,Sn(IV) etiopurpurin

Methylene Violet 3RAX

T77235

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
TN1274	4-Allylcatechol	4-Allylpyrocatechol,Hydroxychavicol	Others
	4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ...		Others
T4S0171	Transcrocetin	trans-Crocetin,8,8'-Diapocarotenedioic Acid,Crocetin	Others , Endogenous Metabolite , iGluR
	Transcrocetin (8,8'-Diapocarotenedioic Acid) is a singlet oxygen quencher.		Others , Endogenous Metabolite , iGluR
T40607	2,4,6-Trimethylphenol	Mesitol	Others
	2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM), is a probe compound that undergoes rapid oxidation by singlet* oxygen in aqueous solutions.		Others
T41242	Uric acid sodium		Reactive Oxygen Species
	Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc...		Reactive Oxygen Species
TN6584	Pallidol
	Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent.
TN4263	Isoangustone A		MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK
	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoang...		MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK
TMA0291	Dehydroglyasperin D		GSK-3 , p38 MAPK , ROS , Akt , COX , PI3K , DNA/RNA Synthesis , Prostaglandin Receptor , JNK
	Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction wit...

Natural Products

Uric Acid

T0626

Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

4-Allylcatechol

TN1274

Synonym: 4-Allylpyrocatechol,Hydroxychavicol

Target: Others

Transcrocetin

T4S0171

Synonym: trans-Crocetin,8,8'-Diapocarotenedioic Acid,Crocetin

Target: Others, Endogenous Metabolite, iGluR

2,4,6-Trimethylphenol

Target: Reactive Oxygen Species

Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK

Dehydroglyasperin D

TMA0291

Synonym:

Target: GSK-3, p38 MAPK, ROS, Akt, COX, PI3K, DNA/RNA Synthesis, Prostaglandin Receptor, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-03403	Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO)	Renilla reniformis	E. coli
	Upon binding the substrate, the enzyme catalyzes an oxygenation, producing a very short-lived hydroperoxide that cyclizes into a dioxetanone structure, which collapses, releasing a CO(2) molecule. The spontaneous breakdo...

Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO)

TMPH-03403

Species: Renilla reniformis

Expression System: E. coli