spermidine

Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). Spermidine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner.

N1,N10-Bis(p-coumaroyl)spermidine, which can be extracted from the herb of alfalfa, exhibits inhibitory effects on alpha-glucosidase.

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine, a compound extractable from Lycium ruthenicum Murr., represents a naturally occurring product. [1]

Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).

Tris(dihydrocaffeoyl)spermidine, an active compound isolated from Solanum tuberosum (potato) tubers, is utilized in metabolism research [1].

Tricoumaroyl spermidine(N1,N5,N10-(Z)-tri-p-coumaroylspermidine) was discovered as unique tea (Camellia sinensis) flower metabolites.

Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

N8-Acetylspermidine dihydrochloride, a polyamine, can be produced in mammals through the acetylation of spermidine by spermidine spermine N1-acetyltransferase (SSAT), followed by subsequent oxidation by [propylamine transferase].

Safflospermidine B is a potential natural tyrosinase inhibitor, it shows high antityrosinase activity (IC50 of 31.8μM).

N1,N5,N10-(E)-tri-p-coumaroylspermidine shows free radical-scavenging activity.

N1,N8-Diacetylspermidine is a polyamine found in human urine.N1,N8-Diacetylspermidine can be used as a marker for cancer and malignancy.

Safflospermidine A is a potential natural tyrosinase inhibitor,it shows high antityrosinase activity (IC50 of 13.8 μM).