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By Target- DNA/RNA Synthesis
- MTH1(2)
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Results for "
th287 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists2
TH287 hydrochloride
T2069L1638211-05-8
TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.
- $46
Size
QTY
TH287
T20691609960-30-6
TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.
- $31
Size
QTY
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