Tryptamine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T124997 and the CAS number is 343-94-2.

5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay). 5-hydroxy-Nω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-Nω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.

Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is recognized to play a role as a neuro

Heterocyclic compound-indole, intermediate and building block

α-Methyltryptamine (hydrochloride), a Schedule I psychedelic drug in the United States, potently promotes monoamine release from synaptosomes while impeding their reuptake, with inhibition concentration 50 (IC50) values of 0.73, 0.38, and 0.4 μM for dopamine, serotonin, and norepinephrine, respectively. This compound is intended for forensic applications.

6-Fluorotryptamine hydrochloride is a compound used as a molecular structural unit and is a derivative of the natural tryptamine alkaloid serotonin. It is an agonist at 5-HT2A and 5-HT2C serotonin receptors, making it a potential candidate for the development of new drugs for the treatment of various psychiatric and neurological disorders.

PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.

Nb-Feruloyltryptamine is a natural product for research related to life sciences. The catalog number is TN6571 and the CAS number is 53905-13-8.

4-Hydroxytryptamine creatinine sulfate, a derivative of tryptamine, acts as an agonist for neurotransmitters.

N-Salicyloyltryptamine(STP) is a tryptamine analogue with anticonvulsant, anti-inflammatory, analgesic, and vasorelaxation effect. N-Salicyloyltryptamine acts as the voltage-dependent Na +, Ca 2+, and K + ion channels inhibitor which inhibits K + currents with an IC 50 value of 34.6 μM ( /to) [1] - [5].

7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer.

5-HT2B receptor agonist

N-Methyltryptamine-d3 is a deuterated compound of N-Methyltryptamine. N-Methyltryptamine has a CAS number of 61-49-4.

5-HT1B agonist

5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.

N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.

N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to melatonin by acetylserotonin O-methyltransferase. It can potently activate TrkB receptor.

5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) is a neurotransmitter.

rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.

5-Methoxy EiPT, a tryptamine-based designer drug, exhibits structural similarity to 5-methoxy DiPT and 5-methoxy MiPT. Although analytical methods for its identification exist, its biological activity remains unreported. This product is intended for forensic and research applications.

RU 27849 is used to study the binding of tryptamine recognition sites.

Rizatriptan sulfate is a selective serotonin 5-HTID receptor agonist derived from tryptamine.

Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraine. Sandomigran is available in number of countries excluding the United States.

Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by tryptamine and hyperthermia induced

5-Methoxy DET, a synthetic tryptamine designer drug, structurally resembles the potent hallucinogen N,N-DMT. It inhibits serotonin uptake (IC50 of 2.4 µM) and activates 5-HT2A receptors (EC50 of 8.11 nM). This compound is designed for forensic and research applications.

CP 132484 is a tryptamine derivative which acts as a potent and selective agonist for the 5-HT₂ family of serotonin receptors. It has reasonable selectivity for 5-HT2A and 5-HT2C subtypes over 5-HT2B, but is only slightly selective for 5-HT2A over 5-HT2C.

BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor K i values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761 is a tryptamine analog with a high affinity for 5-HT(6) receptors, that can enhance long-term memory. BGC20-761 has potential utility as an antipsychotic agent [1].

DPT (hydrochloride), a psychedelic tryptamine class compound, acts by inhibiting dopamine, serotonin, and norepinephrine re-uptake (IC50s = 23, 2.9, and 9.1 μM, respectively). It is designated for research and forensic applications.