vhl ligand 2 hydrochloride

SI-2 hydrochloride (EPH 116 hydrochloride) is a highly promising inhibitor of SRC-3 SMI: SRC-3 (PPI)(IC50 values of 3-20 nM for breast cancer cell death), with acceptable oral availability.

Bis(2-chloroethyl)amine hydrochloride is used as pharmaceutical intermediate.

NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).

2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an EC50 value of 116 nM.

2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride is a cytosine nucleoside analog with inhibitory effects on DNA methyltransferase , with potential antimetabolic and antitumor activity.

4-Benzyl-2-carboxymorpholine hydrochloride is a specialty product for proteomics research applications, from Santa Cruz

AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).

3-(2-aminopropyl)phenol hydrochloride is a phenethylamine analog used as a molecular structural unit. It is a psychoactive drug that is a partial agonist at several serotonin receptors, including 5-HT1A, 5-HT1B, and 5-HT2C, as well as an antagonist at the 5-HT2A receptor.

Bufotenidine hydrochloride(487-91-2 Free base) is a natural product for research related to life sciences. The catalog number is TN7062L and the CAS number is 40581-89-3.

AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and migration of human cancer cell lines (UMUC3, T24, A549).

A2B receptor antagonist 2 hydrochloride is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).

2-PADQZ hydrochloride shows antiviral activity and targets influenza A virus RNA promoter.

(1R,2R)-2-PCCA hydrochloride is a potent, selective, and blood-brain-barrier-crossing GPR88 receptor agonist with an EC50 value of 1140 n in striatal membranes of WT mice.(1R,2R)-2-PCCA hydrochloride can be used to study the central nervous system.

(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.

5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT , is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. [1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotonin binding sites. Journal of Medicinal Chemistry, 1989;32(1), 253-256.

CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders.

SNIPER(TACC3)-2 hydrochloride is a compound that induces degradation of the TACC3 protein through the ubiquitin-proteasome pathway by exploiting an IAP ligand, leading to the induction of cancer cell death [1].

(R)-1-Amino-3-chloro-2-propanol hydrochloride is a biochemical.

Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.

TSPO ligand-2 (Carbonic acid) is a ligand of AUTAC1 which contains a p-fluorobenzylguanine and a Fumagillol moiety.

SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.

GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).

VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, including the notable ARD-266. ARD-266 is an exceptionally effective androgen receptor (AR) PROTAC degrader[1].

CBP/p300 ligand 2 is a selective ligand that binds to the target protein for PROTAC of dCBP-1, a potent and selective heterobifunctional degrader of p300/CBP.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-morpholinoethyl)-, hydrochloride is a bioactive chemical.

cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.

Methyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65280 and the CAS number is 482577-59-3.

1-(2-Chloroethyl)piperidine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66881 and the CAS number is 2008-75-5.

Carbanilic acid, m-heptyloxy-, 2-(dimethylamino)ethyl ester, hydrochloride is a bioactive chemical.

2-((Dimethylamino)methyl)cyclohexanone hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67214 and the CAS number is 42036-65-7.

SMARCA-BD Ligand 1 Hydrochloride, used in PROTAC technology, targets and binds to the BAF ATPase subunits SMARCA2, facilitating its degradation.

1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66538 and the CAS number is 223251-25-0.

(S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65272 and the CAS number is 14328-62-2.

Octyl 2-aminoacetate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65113 and the CAS number is 39540-30-2.

(S)-Pyrrolidine-2-carboxamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67652 and the CAS number is 42429-27-6.

m-Acetotoluidide, 6'-chloro-2-(diethylamino)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-((hexyloxy)methyl)-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67443 and the CAS number is 127337-60-4.

Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66601 and the CAS number is 1243308-37-3.

(S)-3-Amino-1-chloro-5-methylhexan-2-one hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65276 and the CAS number is 54518-92-2.

2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64780 and the CAS number is 4876-14-6.

(S)-Pyrrolidine-2-carboxylic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66349 and the CAS number is 7776-34-3.

(S)-Methyl 2-amino-3-cyclohexylpropanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66551 and the CAS number is 17193-39-4.

5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66095 and the CAS number is 720720-96-7.

m-Acetotoluidide, 6'-chloro-2-(diethylamino)-alpha,alpha,alpha-trifluoro-, hydrochloride is a bioactive chemical.

(S)-Ethyl 2-dodecanamido-5-guanidinopentanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67230 and the CAS number is 60372-77-2.

(S)-tert-Butyl 2-amino-4-methylpentanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65115 and the CAS number is 2748-02-9.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Amino nucleosides; 2’-Modified nucleosides

2-(Methylamino)acetic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65425 and the CAS number is 637-96-7.

Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, hydrochloride is a bioactive chemical.