CETP

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Most of the time, however, CETP does a heteroexchange, trading a triglyceride for a cholesteryl ester or a cholesteryl ester for a triglyceride.

Cat No.	product name
T13079	TAP311	TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).
T13423	(1R,2R)-2-PCCA(hydrochloride)	(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and is a potent agonist of GPR88 receptor(EC50 of 3 nM and 603 nM in cell-free assay and in cell assay...
T15004	CP-532623	CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.
T15570	Implitapide	Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T16266	NAMI-A	NAMI-A is a ruthenium-based drug characterized by the selective activity against tumor metastases. NAMI-A inhibits adhesion and migration.
T1928	Anacetrapib	Anacetrapib (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer o...
T2499	Torcetrapib	Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Tor...
T2545	Lomitapide Mesylate	Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
T4S2157	Campesterol	Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. ...
T6048	Dalcetrapib	Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
T6262	Evacetrapib	Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pres...
T6267	Lomitapide	Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsi...

Cat No.

product name

T13079

TAP311

TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).

T13423

(1R,2R)-2-PCCA(hydrochloride)

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and is a potent agonist of GPR88 receptor(EC50 of 3 nM and 603 nM in cell-free assay and in cell assay...

T15004

CP-532623

CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.

T15570

Implitapide

Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).

T16266

NAMI-A

NAMI-A is a ruthenium-based drug characterized by the selective activity against tumor metastases. NAMI-A inhibits adhesion and migration.

T1928

Anacetrapib

Anacetrapib (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer o...

T2499

Torcetrapib

Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Tor...

T2545

Lomitapide Mesylate

Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.

T4S2157

Campesterol

Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. ...

T6048

Dalcetrapib

Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.

T6262

Evacetrapib

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pres...

T6267

Lomitapide

Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsi...