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OCT

Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene. Oct-4 is a homeodomain transcription factor of the POU family. It is critically involved in the self-renewal of undifferentiated embryonic stem cells. As such, it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN2147 Retrorsine 480-54-6 98%
Retrorsine
Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the...
T4912 Jatrorrhizine chloride 6681-15-8 99.79%
Jatrorrhizine chloride
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-ind...
T2019 OAC2 6019-39-2 99.76%
OAC2
OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of in...
T3221 Oct3/4-inducer-1 1016535-83-3 99%
Oct3/4-inducer-1
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its tr...
TN1237 3-O-Methylgallic acid 3934-84-7 98.53%
3-O-Methylgallic acid
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may...
T2040 OAC1 300586-90-7 97.38%
OAC1
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the rep...
T2439 O4I1 175135-47-4 96.25%
O4I1
O4I1 is an effective Oct3/4 inducer.
T2437 O4I2 165682-93-9 98%
O4I2
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
Retrorsine
TN2147
Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the...
Jatrorrhizine chloride
T4912
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-ind...
OAC2
T2019
OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of in...
Oct3/4-inducer-1
T3221
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its tr...
3-O-Methylgallic acid
TN1237
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may...
OAC1
T2040
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the rep...
O4I1
T2439
O4I1 is an effective Oct3/4 inducer.
O4I2
T2437
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
TargetMol