T2751 |
Ginkgolide B |
Ginkgolide B is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba. |
T6242 |
Rupatadine Fumarate |
Rupatadine Fumarate (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM. |
T3856 |
Tenuifoliside A |
Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF...
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TN1170 |
1-Cinnamoylpyrrolidine |
1-Cinnamoylpyrrolidine shows inhibitory activity of platelet aggregation in vitro. |
TN1254 |
3'-Methoxydaidzein |
3'-Methoxydaidzein has antioxidant activity, it and geraldol have antiplatelet aggregation activity and appear to be specific against collageninduce platele...
|
TN1271 |
4',5,6,7-Tetramethoxyflavone |
4',5,6,7-Tetramethoxyflavone has a hemostatic effect. |
TN1643 |
Ferulamide |
Ferulamide derivatives show potent inhibitory activity against arachidonic acid-induced platelet aggregation. |
TN1715 |
Guaiacin |
(+)-Guaiacin has significant neuroprotective, and anti-inflammatory activities, it can inhibit cyclooxygenase (COX)-1 and COX-2. |
TN1815 |
Kadsulignan L |
Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC...
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TN1873 |
Lirinidine |
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesi...
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TN2086 |
Piperlotine A |
Piperlotine A shows potent antiplatelet aggregation activity. |
TN2087 |
Piperlotine C |
Piperlotine C shows potent antiplatelet aggregation activity. |
TN2322 |
Yangambin |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a per...
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TN2329 |
Zingiberen newsaponin |
Zingiberensis newsaponin I exhibits induction effect on platelet aggregation. |
TN1654 |
Futoquinol |
Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng. |
T3P2855 |
Chamigrenal |
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7...
|
TL0014 |
Pinusolide |
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, ...
|
TMA2418 |
1-Methoxyphaseollidin |
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Met...
|
TN2763 |
2-Hydroxy-3-methoxybenzoic acid glucose ester |
2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PA...
|
TN3153 |
6-Acetyl-2,2-dimethylchroman-4-one |
6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro. |
TN3161 |
6-Deoxyjacareubin |
6-Deoxyjacareubin possesses significant antioxidant activities, it also exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cel...
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TN3348 |
Acuminatin |
(-)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity a...
|
TN3443 |
Aristolactam AII |
Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity. |
TN3445 |
Aristolactam BIII |
Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388,...
|
TN3520 |
Bisdethiobis(methylthio)gliotoxin |
Bisdethiobis(methylthio)gliotoxin is a platelet activating factor (PAF) antagonist. |
TN3723 |
Cryptomeridiol |
Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low a...
|
TN3740 |
Cyclocommunol |
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong i...
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TN3831 |
Denudatin B |
Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin, it inhibits th...
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TN3979 |
Epiyangambin |
Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of La...
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TN4088 |
Futoenone |
Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases, the molecular modelings of these compounds indicat...
|
TN4181 |
Hancinone C |
Hancinone C shows inhibitory activity against the platelet aggregation caused by PAF. |
TN4367 |
Kadsurin A |
Kadsurin A and Kadsurin B have anti-platelet activating factor activities. |
TN4600 |
Myrianthic acid |
Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low...
|
TN4660 |
Niranthin |
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competiti...
|
TN4794 |
Pinusolidic acid |
Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 microgra...
|
TN4795 |
Piperenone |
Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist. |
TN4796 |
Piperlotine D |
Piperlotine D shows potent antiplatelet aggregation activity. |
TN4797 |
Piperolactam C |
Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides. |
TN4821 |
Pregomisin |
Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M. |
TN5045 |
Spiradine F |
Spiradine F can significantly inhibit platelet-activating factor(PAF)-induced platelet aggregation in a concentration-dependent manner. |