PAFR

The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor. The PAF receptor shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.[supplied by OMIM][7] Its pathogenetic role in chronic kidney failure has also been reported recently.

Cat. No.	Product name	CAS No.	Purity
T3P2855	Chamigrenal	19912-84-6	98%
T3P2855	β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
TN4795	Piperenone	57625-31-7	98%
TN4795	Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.
TN4797	Piperolactam C	116064-76-7	98%
TN4797	Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides.
TN4796	Piperlotine D	958296-13-4	98%
TN4796	Piperlotine D shows potent antiplatelet aggregation activity.
TN4794	Pinusolidic acid	40433-82-7	98%
TN4794	Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 microgram...
TN3348	(+)-Acuminatin	41744-39-2	98%
TN3348	(-)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity ag...
TN2763	2-Hydroxy-3-methoxybenzoic acid glucose ester	172377-87-6	98%
TN2763	2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF...
TN3153	6-Acetyl-2,2-dimethylchroman-4-one	68799-41-7	98%
TN3153	6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro.
TN1654	Futoquinol	28178-92-9	98%
TN1654	Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng.
TN3445	Aristolactam BIII	53948-10-0	98%
TN3445	Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, ...
TN3723	Cryptomeridiol	4666-84-6	98%
TN3723	Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low act...
TL0014	Pinusolide	31685-80-0	98%
TL0014	Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
TN3161	6-Deoxyjacareubin	16265-56-8	98%
TN3161	6-Deoxyjacareubin exhibits potent antioxidant and antifungal activities. 6-Deoxyjacareubin inhibits platelet activating factor (PAF) receptor with an IC50 of 29....
TMA2418	1-Methoxyphaseollidin	65428-13-9	98%
TMA2418	1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Meth...
TN4600	Myrianthic acid	89786-84-5	98%
TN4600	Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-...
TN4821	Pregomisin	66280-26-0	98%
TN4821	Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M.
TN2087	Piperlotine C	886989-88-4	98%
TN2087	Piperlotine C shows potent antiplatelet aggregation activity.
TN3740	Cyclocommunol	145643-96-5	98%
TN3740	Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong in...
TN4367	Kadsurin A	99340-07-5	98%
TN4367	Kadsurin A has anti-platelet activating factor activities.
TN3979	Epiyangambin	24192-64-1	98%
TN3979	Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lac...