PTEN

Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers. Genes corresponding to PTEN (orthologs) have been identified in most mammals for which complete genome data are available. PTEN acts as a tumor suppressor gene through the action of its phosphatase protein product. This phosphatase is involved in the regulation of the cell cycle, preventing cells from growing and dividing too rapidly. It is a target of many anticancer drugs.

Cat. No.	Product name	CAS No.	Purity
T10594	BpV(phen)	42494-73-5	98%
bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).
T7012	VO-Ohpic trihydrate	476310-60-8	98%
VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
TP1072	Valinomycin	2001-95-8	98%
Valinomycin is a dodecadepsipeptide antibiotic, which is obtained from several Streptomyces strains. Valinomycin functions as a potassium-specific transporter an...
T3780	Oroxin B	114482-86-9	98%
Oroxin B has antioxidant activity.
T6667	SF1670	345630-40-2	98%
SF1670 is a specific PTEN inhibitor with IC50 of 2 μM.
T3404	Cucurbitacin B	6199-67-3	98%
Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-reg...
TN1362	Afzelin	482-39-3	98%
Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protec...
T6S2116	Ginkgolic acid C17:1	111047-30-4	98%
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, an...
T7953	BpV(HOpic)	722494-26-0	98%
bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T10594

BpV(phen)

42494-73-5

98%

bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).

T7012

VO-Ohpic trihydrate

476310-60-8

98%

VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.

TP1072

Valinomycin

2001-95-8

98%

Valinomycin is a dodecadepsipeptide antibiotic, which is obtained from several Streptomyces strains. Valinomycin functions as a potassium-specific transporter an...

T3780

Oroxin B

114482-86-9

98%

Oroxin B has antioxidant activity.

T6667

SF1670

345630-40-2

98%

SF1670 is a specific PTEN inhibitor with IC50 of 2 μM.

T3404

Cucurbitacin B

6199-67-3

98%

Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-reg...

TN1362

Afzelin

482-39-3

98%

Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protec...

T6S2116

Ginkgolic acid C17:1

111047-30-4

98%

1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, an...

T7953

BpV(HOpic)

722494-26-0

98%

bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).