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PTEN

Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers. Genes corresponding to PTEN (orthologs) have been identified in most mammals for which complete genome data are available. PTEN acts as a tumor suppressor gene through the action of its phosphatase protein product. This phosphatase is involved in the regulation of the cell cycle, preventing cells from growing and dividing too rapidly. It is a target of many anticancer drugs.
Cat No. product name
TN1362 Afzelin Afzelin 具有多种细胞活性,例如 DNA 保护、抗菌、抗氧化和抗炎以及 UV 吸收活性,并且可以通过 UV 吸收和细胞活性的组合保护人体皮肤免受 UVB 引起的损伤。 Afzelin 减轻线粒体损伤,增强线粒体生物合成并降低线粒体自噬相关蛋白、parkin 和 putative kinase 1 的水平。
T3404 Cucurbitacin B Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-reg...
T6S2116 Ginkgolic acid C17:1 1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, an...
T3780 Oroxin B Oroxin B has antioxidant activity.
T7012 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
TP1072 Valinomycin Valinomycin is a dodecadepsipeptide antibiotic, which is obtained from several Streptomyces strains. Valinomycin functions as a potassium-specific transporter an...
T6667 SF1670 SF1670 is a specific PTEN inhibitor with IC50 of 2 μM.
T7953 BpV(HOpic) bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).
T10594 BpV(phen) bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).
Afzelin
TN1362
Cucurbitacin B
T3404
Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-reg...
Ginkgolic acid C17:1
T6S2116
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, an...
Oroxin B
T3780
Oroxin B has antioxidant activity.
VO-Ohpic trihydrate
T7012
VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Valinomycin
TP1072
Valinomycin is a dodecadepsipeptide antibiotic, which is obtained from several Streptomyces strains. Valinomycin functions as a potassium-specific transporter an...
SF1670
T6667
SF1670 is a specific PTEN inhibitor with IC50 of 2 μM.
BpV(HOpic)
T7953
bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).
bpV(phen)
T10594
bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).