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Colony-Stimulating Factors, CSFs

Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of committed progenitors in the bone marrow, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate into a specific kind of blood cell (usually white blood cells). The name "colony-stimulating factors" comes from the method by which they were discovered. The substance that was found to stimulate formation of colonies of macrophages, for instance, was called macrophage CSFs, for granulocytes, granulocyte CSFs, and so on. Colony-stimulating factors include: macrophage CSFs (CSF1), Granulocyte macrophage CSFs (CSF2, also called GM-CSF and sargramostim), Granulocyte CSFs (CSF3, also called G-CSF and filgrastim), Interleukin 3 etc.

  • GM-CSF/CSF2 Protein, Human, Recombinant
    TMPY-03858
    GM-CSF/CSF2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
    • $136
    In Stock
    Size
    QTY
  • G-CSF Protein, Mouse, Recombinant
    TMPY-05636
    G-CSF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19 kDa and the accession number is P09920.
    • $177
    In Stock
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant (His)
    TMPJ-00327
    Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
    • $118
    In Stock
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant (His & Avi)
    TMPK-00323
    CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. M-CSF/CSF1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is P09603-1.
    • $698
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His)
    TMPK-01325
    M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.26 kDa and the accession number is XP_045221641.1.
    • $394
    7-10 days
    Size
    QTY
  • GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)
    TMPJ-01465
    Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.
    • $92
    In Stock
    Size
    QTY
  • M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
    TMPY-04704
    M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.1 kDa and the accession number is XP_005542489.1.
    • $695
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Mouse, Recombinant (His)
    TMPY-03537
    M-CSF/CSF1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P07141-1.
    • $539
    In Stock
    Size
    QTY
  • GM-CSF/CSF2 Protein, Rat, Recombinant (His)
    TMPY-03713
    GM-CSF/CSF2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P48750.
    • $197
    In Stock
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant (aa 33-190)
    TMPK-00322
    M-CSF/CSF1 Protein, Human, Recombinant (aa 33-190) is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is P09603-1.
    • $581
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00324
    CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. M-CSF/CSF1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is P09603-1.
    • $1,400
    7-10 days
    Size
    QTY
  • G-CSF Protein, Canine, Recombinant (His & SUMO)
    TMPH-00490
    G-CSF Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
    • $360
    20 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant
    TMPY-00127
    M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
    • $275
    In Stock
    Size
    QTY
  • G-CSF Protein, Human, Recombinant (hFc)
    TMPY-00813
    G-CSF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P09919-2.
    • $773
    7-10 days
    Size
    QTY
  • GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc)
    TMPY-03631
    GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01587.
    • $306
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (His)
    TMPY-04705
    M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.8 kDa and the accession number is XP_005542489.1.
    • $695
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant, Biotinylated
    TMPY-05181
    M-CSF/CSF1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
    • $383
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant (His), Biotinylated
    TMPY-05335
    M-CSF/CSF1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.8 kDa and the accession number is P09603-1.
    • $383
    7-10 days
    Size
    QTY
  • GM-CSF/CSF2 Protein, Mouse, Recombinant
    TMPY-04114
    GM-CSF/CSF2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is P01587.
    • $106
    In Stock
    Size
    QTY
  • M-CSF/CSF1 Protein, Human, Recombinant (hFc)
    TMPY-04229
    M-CSF/CSF1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.9 kDa and the accession number is P09603-2.
    • $695
    7-10 days
    Size
    QTY
  • G-CSF Protein, Human, Recombinant
    TMPY-04829
    G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
    • $205
    In Stock
    Size
    QTY
  • GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated
    TMPY-05236
    GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
    • $383
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Mouse, Recombinant
    TMPY-00464
    M-CSF/CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1.
    • $177
    In Stock
    Size
    QTY
  • G-CSF Protein, Mouse, Recombinant (His)
    TMPJ-00091
    Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.
    • $184
    7-10 days
    Size
    QTY
  • GM-CSF/CSF2 Protein, Human, Recombinant (hFc)
    TMPY-00750
    GM-CSF/CSF2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is P04141.
    • $447
    In Stock
    Size
    QTY
  • GM-CSF/CSF2 Protein, Human, Recombinant (His)
    TMPY-02466
    GM-CSF/CSF2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P04141.
    • $695
    7-10 days
    Size
    QTY
  • GM-CSF/CSF2 Protein, Mouse, Recombinant (His)
    TMPY-03662
    GM-CSF/CSF2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.10 kDa and the accession number is P01587.
    • $178
    In Stock
    Size
    QTY
  • GM-CSF/CSF2 Protein, Rat, Recombinant (hFc)
    TMPY-04036
    GM-CSF/CSF2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P48750.
    • $306
    7-10 days
    Size
    QTY
  • M-CSF/CSF1 Protein, Rat, Recombinant
    TMPJ-01218
    Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
    • $184
    7-10 days
    Size
    QTY