Fibroblast Growth Factor Receptors, FGFRs

The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.

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FGFR4 Protein, Human, Recombinant (hFc)

TMPY-00806

FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1.

$600

7-10 days

Size

QTY

FGFR4 Protein, Mouse, Recombinant (His & hFc)

TMPY-01019

FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the accession number is A0A0R4IZY3.

$600

7-10 days

Size

QTY

FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

TMPY-06036

FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.

$228

In Stock

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FGFR1 Protein, Human, Recombinant (beta (IIIb), His)

TMPY-06034

FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4.

$583

In Stock

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QTY

FGFR2 Protein, Mouse, Recombinant (His)

TMPY-03389

FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1.

$600

7-10 days

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QTY

FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)

TMPK-00847

FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2.

$487

7-10 days

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QTY

FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

TMPJ-00391

FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.

7-10 days

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QTY

FGFR4 Protein, Human, Recombinant (His & Avi)

TMPK-00379

FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.

$231

7-10 days

Size

QTY

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

TMPK-00384

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.

$347

7-10 days

Size

QTY

FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)

TMPK-00686

FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9.

$418

7-10 days

Size

QTY

FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00381

FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.

$814

7-10 days

Size

QTY

FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00380

FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.

$814

7-10 days

Size

QTY

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00391

Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.

$814

7-10 days

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QTY

FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00401

Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.

$814

7-10 days

Size

QTY

FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

TMPK-00392

Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession number is P11362-7.

$347

7-10 days

Size

QTY

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

TMPK-00398

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.

$534

7-10 days

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QTY

FGFR4 Protein, Mouse, Recombinant (His)

TMPY-00974

FGFR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0A0R4IZY3.

$700

7-10 days

Size

QTY

FGFR2 Protein, Human, Recombinant (His & hFc)

TMPY-00972

FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1.

$386

In Stock

Size

QTY

FGFR4 Protein, Human, Recombinant (His)

TMPY-02112

FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.

$255

In Stock

Size

QTY

FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)

TMPY-06033

FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is H9FRD4.

$904

7-10 days

Size

QTY

FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00394

Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession number is P11362-7.

$814

7-10 days

Size

QTY

FGFR2IIIc Protein, Human, Recombinant (hFc)

TMPJ-00388

FGFR2IIIc Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802.

7-10 days

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FGFR1 Protein, Human, Recombinant (Yeast, His)

TMPH-01337

FGFR1 Protein, Human, Recombinant (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P11362.

$231

20 days

Size

QTY

FGFR2 Protein, Human, Recombinant (beta IIIc, His)

TMPY-00351

FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is P21802-21.

$904

7-10 days

Size

QTY

FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)

TMPY-00423

FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17.

$583

In Stock

Size

QTY

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)

TMPK-00389

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa and the accession number is P22607-2.

$418

7-10 days

Size

QTY

FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)

TMPK-00385

FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P22607-1.

$418

7-10 days

Size

QTY

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00386

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.

$814

7-10 days

Size

QTY

FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)

TMPK-00388

FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.

$347

7-10 days

Size

QTY

FGFRL1 Protein, Human, Recombinant (His)

TMPJ-01224

Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.

7-10 days

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FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)

TMPY-00389

FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is P22607-2.

$904

7-10 days

Size

QTY

FGFR2 Protein, Human, Recombinant (aa 1-377, His)

TMPY-01228

FGFR2 Protein, Human, Recombinant (aa 1-377, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41 kDa and the accession number is P21802-1.

$600

7-10 days

Size

QTY

FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

TMPY-06035

FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7.

$904

7-10 days

Size

QTY

FGFR4 Protein, Rhesus, Recombinant (His)

TMPY-03683

FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number is XP_001087243.1.

$600

7-10 days

Size

QTY

FGFR1 Protein, Human, Recombinant (His & GST)

TMPY-04371

FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is H9FRD4.

$498

7-10 days

Size

QTY

FGFR1 Protein, Rhesus, Recombinant (His)

TMPY-03926

FGFR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is H9FRD4.

$600

7-10 days

Size

QTY

FGFR3 Protein, Human, Recombinant (hFc)

TMPY-04200

FGFR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is P22607-1.

$904

7-10 days

Size

QTY

FGFR1 Protein, Human, Recombinant (His), Biotinylated

TMPY-05761

FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4.

$306

7-10 days

Size

QTY

FGFR1 Protein, Human, Recombinant (hFc)

TMPY-05777

FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number is NP_001341297.1.

$357

7-10 days

Size

QTY

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

TMPK-00393

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.

$231

7-10 days

Size

QTY

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

TMPK-00399

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.

$814

7-10 days

Size

QTY

FGFR2IIIb Protein, Human, Recombinant (hFc)

TMPJ-00390

FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.

7-10 days

Size

QTY

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00395

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.

$814

7-10 days

Size

QTY

FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00396

FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42.5 kDa and the accession number is P21802-1.

$814

7-10 days

Size

QTY

FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00400

FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3.

$814

7-10 days

Size

QTY

FGFR1 Protein, Mouse, Recombinant (His)

TMPY-01781

FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number is P16092-1.

$700

7-10 days

Size

QTY

FGFR1 Protein, Mouse, Recombinant (hFc)

TMPY-01782

FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number is P16092-1.

$700

7-10 days

Size

QTY

FGFR4 Protein, Rat, Recombinant (hFc)

TMPY-02635

FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q498D6.

$600

7-10 days

Size

QTY

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