c-2-8

8-Glucosyl-5,7-dihydroxy-2-isopropylchromone is a natural product for research related to life sciences. The catalog number is TN5698 and the CAS number is 188785-44-6.

Apigenin 6-C-(2-O-feruloyl)glucoside 8-C-glucoside is a useful organic compound for research related to life sciences and the catalog number is T126101.

8-C-(2-Rhamnosyl-6-deoxyhexopyranosulyl)luteolin is a useful organic compound for research related to life sciences. The catalog number is T123914 and the CAS number is 933463-03-7.

Compound 1059182-21-6 features a cyclic structure characterized by a nitrogen atom occupying an apex (corner) within the heterocycle. Its molecular scaffold integrates aromatic properties due to the presence of a conjugated system, while the inclusion of hydroxyl (-OH) groups confers reactive potential for subsequent modification. Additionally, a halogenated component, specifically a bromine atom, is attached to the aromatic ring, enhancing its propensity for undergoing further synthetic transformations.

Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-xylopyranoside is a natural product from Viola yedoensis.

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin compound present in Heracleum pyrenaicum Lam.

Ajugasterone C 2-acetate, an ecdysteroid extractable from Cyanotis arachnoidea [1], is a chemical compound.

Formononetin-8-C-beta-D-apiofuranosyl-(1->6)-O-beta-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN6636 and the CAS number is 1147858-78-3.

Apigenin-6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside, a flavonoid known for its antioxidant activity, can be isolated from the Traditional Chinese Medicine TiepiShihu [1].

8-Hydroxy-9,10-diisobutyryloxy-thymol, a potent terpenoid found in Inula sericophylla [1], exhibits significant bioactivity.

Chrysin 8-C-glucoside is a natural product for research related to life sciences. The catalog number is TN3649 and the CAS number is 160880-89-7.

8-C-Glucosyl-(R)-aloesol ((R)-Aloesinol) is a bioactive analogue of chromone [1].

Aristola-1(10),8-dien-2-one is a natural product. The catalog number is TN3442 and the CAS number is 22391-34-0. Aristola-1(10),8-dien-2-one can be used as a reference standard.

2',4'-Dihydroxy-7-methoxy-8-prenylflavan is a natural product for research related to life sciences. The catalog number is TN2720 and the CAS number is 331954-16-6.

8-(3-Ethoxy-2-hydroxy-3-methylbutyl)-5,7-dimethoxy-2H-chromen-2-one is a naturally occurring compound isolated from the roots of Murraya exotica [1].

2-C-Methyl-D-erythritol is a natural product from the fruit of Carum ajowan

(-)-2-C-Methyl-D-erythrono-1,4-lactone is inactive alone, but elicits oviposition behavior when mixes with other fractions.

Vitexin-2 -O-rhamnoside (Apigenin-8-C-glucoside) is a compound contributes to the protection against H O -mediated oxidative stress damage.

Orientin 2''-O-rhamnoside is a natural product for research related to life sciences. The catalog number is TN5525 and the CAS number is 81398-30-3.

Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.

Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.

8-(1,1-Dimethyl-2-propenyl)-3'-methoxykaempferol is a natural product for research related to life sciences. The catalog number is TN5521 and the CAS number is 1859979-00-2.

1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone exhibits strong antibacterial properties, demonstrating an MIC 50 of 22 µM and an MIC 90 of 50 µM against Helicobacter pylori Strain 51. This compound shows promise for research into gastric and duodenal ulcers [1].

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole is a natural product for research related to life sciences. The catalog number is TN6194 and the CAS number is 484678-79-7.

2-Methoxyfuranoguaia-9-ene-8-one is a natural product for research related to life sciences. The catalog number is TN6585 and the CAS number is 88010-62-2.

(R)-Eriodictyol-8-C-beta-D-glucopyranoside is a useful organic compound for research related to life sciences and the catalog number is T126514.

3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is a natural product

8-(1,1-Dimethyl-2-propenyl)kaempferol is a natural product for research related to life sciences. The catalog number is TN5519 and the CAS number is 142646-43-3.

8beta-(2-Hydroxy-2-methyl-3-oxobutyryloxy)glucozaluzanin C is a natural product for research related to life sciences. The catalog number is TN3301 and the CAS number is 93395-31-4.

8-C-Galactosylluteolin is a useful organic compound for research related to life sciences. The catalog number is T124540 and the CAS number is 61950-88-7.

8-Glucosyl-5,7-dihydroxy-2-(1-methylpropyl)chromone is a natural product for research related to life sciences. The catalog number is TN3278 and the CAS number is 188818-27-1.

8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen is a natural product for research related to life sciences. The catalog number is TN6298 and the CAS number is 889112-17-8.

8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro.

2''-O-Acetylsprengerinin C is a natural product for research related to life sciences. The catalog number is TN2782 and the CAS number is 1220707-33-4.

2'-O-Methylbroussonin C is a natural product for research related to life sciences. The catalog number is TN2499 and the CAS number is 376362-03-7.

Genistein 8-c-glucoside (G8CG) induces mitochondrial membrane depolarization and induces apoptosis. Genistein 8-c-glucoside (G8CG) is a natural glucoside isolated from flowers of Lupinus luteus L.

8-Daucene-2,4,6-triol, O-(4-Hydroxybenzoyl), 2-Ac is a useful organic compound for research related to life sciences and the catalog number is T130945.

Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate is a natural product for research related to life sciences. The catalog number is TN4537 and the CAS number is 96287-41-1.

8-Chloro-2-(2-phenylethyl)-5,6,7-trihydroxy-5,6,7,8-tetrahydrochromone, a chromone derivative, is present in the methanol extract obtained from withered wood of Aquilaria sinensis.

8-Methoxyfissistigine C is a natural product for research related to life sciences. The catalog number is TN6082 and the CAS number is 20824-18-4.

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.

2',5,7-Trihydroxy-8-methoxyflavanone has cytotoxic activity.

8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin is a natural product for research related to life sciences. The catalog number is TN3259 and the CAS number is 131652-35-2.

7-Methoxy-8-(3-methyl-2-oxobutoxy)-2H-1-benzopyran is a useful organic compound for research related to life sciences. The catalog number is T125498 and the CAS number is 188426-72-4.

Detigloylswietenine, 2-Hydroxy, 8?,30?-epoxide, 3- is a useful organic compound for research related to life sciences and the catalog number is T130051.

ALPHA-PINENE ((-)-Alpha-Pinene) is a bicyclic monoterpene found in pine trees and other plants, including Cannabis with diverse biological activities [1]. It reduces the growth of a panel of seven Gram-positive bacteria, seven Gram-negative bacteria, and eight yeast strains with MIC values of 0.75-1.29, 1.05-1.59, and 0.7-1.17%, respectively [2]. It has insecticidal activity against C. molestus larvae with LC50 values ranging from 47 to 49 mg/L.3 ALPHA-PINENE (100 μg/ml) induces apoptosis, increases anion superoxide production and DNA fragmentation, and activates caspase-3 in B16/F10 melanoma cells [4]. In a B16/F10 mouse xenograft model, ALPHA-PINENE(100 ml of a 10 mg/ml solution) reduces the number of metastatic lung nodules by approximately 7-fold. ALPHA-PINENE(8.6 mg/L, aerosol) also increases the time spent in the open arms of the elevated plus maze by approximately 2-fold in mice, indicating anxiolytic-like activity [5].

1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin and swertiamarin show significant hepatoprotective effect in the liver damage model induced by alpha-naphthylisot hiocyanate. 3. Swertianolin shows anti-acetylcholinesterase activity effects. 4. Swertianolin shows that it can scavenge superoxide and hydroxyl radicals with the studying method of the autoxidation of Pyrogallol and afenton.

Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nemorosone also inhibits growth of Capan-1, AsPC-1, and MIA-PaCa-2 pancreatic cancer cells (IC50s = 4.5-5.0 μM following a 72-hour treatment) but not human dermal and foreskin fibroblasts (IC50s = >35 μM).1 It induces apoptosis, abolishes the mitochondrial membrane potential, and increases cytosolic calcium concentration in pancreatic cancer cells in a dose-dependent manner. Nemorosone activates the caspase cascade in a dose-dependent manner and inhibits cell cycle progression, increasing the proportion of cells in the G0/G1 phase, in both neuroblastoma and pancreatic cancer cells.1,2 Nemorosone (50 mg/kg, i.p., per day) also reduces tumor growth in an MIA-PaCa-2 mouse xenograft model.3References1. Holtrup, F., Bauer, A., Fellenberg, K., et al. Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR). Br. J. Pharmacol. 162(5), 1045-1059 (2011).2. Díaz-Carballo, D., Malak, S., Bardenheuer, W., et al. Cytotoxic activity of nemorosone in neuroblastoma cells. J. Cell. Mol. Med. 12(6B), 2598-2608 (2008).3. Wold, R.J., Hilger, R.A., Hoheisel, J.D., et al. In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts. PLoS One 8(9), e74555 (2013). Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nemorosone also inhibits growth of Capan-1, AsPC-1, and MIA-PaCa-2 pancreatic cancer cells (IC50s = 4.5-5.0 μM following a 72-hour treatment) but not human dermal and foreskin fibroblasts (IC50s = >35 μM).1 It induces apoptosis, abolishes the mitochondrial membrane potential, and increases cytosolic calcium concentration in pancreatic cancer cells in a dose-dependent manner. Nemorosone activates the caspase cascade in a dose-dependent manner and inhibits cell cycle progression, increasing the proportion of cells in the G0/G1 phase, in both neuroblastoma and pancreatic cancer cells.1,2 Nemorosone (50 mg/kg, i.p., per day) also reduces tumor growth in an MIA-PaCa-2 mouse xenograft model.3 References1. Holtrup, F., Bauer, A., Fellenberg, K., et al. Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR). Br. J. Pharmacol. 162(5), 1045-1059 (2011).2. Díaz-Carballo, D., Malak, S., Bardenheuer, W., et al. Cytotoxic activity of nemorosone in neuroblastoma cells. J. Cell. Mol. Med. 12(6B), 2598-2608 (2008).3. Wold, R.J., Hilger, R.A., Hoheisel, J.D., et al. In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts. PLoS One 8(9), e74555 (2013).

Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), but not HeLa cell orE. coli, DNA polymerase (IC50s = 75, 610, and >700 μM, respectively).5It is active against the bacteriumS. pneumoniae(MIC = 32 μg/ml) and the plant pathogenic fungusP. infestans(MIC = 16 μM).1,6 1.Wainwright, M., Betts, R.P., and Teale, D.M.Antibiotic activity of oosporein from Verticillium psalliotaeTrans. Br. Mycol. Soc.86(1)168-170(1986) 2.Jeffs, L.B., and Khachatourians, G.G.Toxic properties of Beauveria pigments on erythrocyte membranesToxicon. 35(8)1351-1356(1997) 3.Arboleda Valencia, J.W., Gaitán Bustamante, A.L., Jiménez, A.V., et al.Cytotoxic activity of fungal metabolites from the pathogenic fungus Beauveria bassiana: An intraspecific evaluation of beauvericin productionCurr. Microbiol.63(3)306-312(2011) 4.Cole, R.J., Kirksey, J.W., Cutler, H.G., et al.Toxic effects of oosporein from Chaetomium trilateraleJ. Agric. Food Chem.22(3)517-520(1974) 5.Terry, B.J., Liu, W.C., Cianci, C.W., et al.Inhibition of herpes simplex virus type 1 DNA polymerase by the natural product oosporeinJ. Antibiot. (Tokyo)45(2)286-288(1992) 6.Nagaoka, T., Nakata, K., Kouno, K., et al.Antifungal activity of oosporein from an antagonistic fungus against Phytophthora infestansZ. Naturforsch. C. J. Biosci.59(3-4)302-304(2004)

Yuehgesin C is a natural product for research related to life sciences. The catalog number is TN3265 and the CAS number is 125072-68-6.