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Results for "

fty720 phosphate

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    9
    TargetMol | Activity
  • Natural Products
    2
    TargetMol | inventory
  • Isotope Products
    1
    TargetMol | natural
FTY720 (S)-Phosphate
T15354402616-26-6
FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in research on acute inflammatory diseases, including acute lung injury.
  • $1,710
8-10 weeks
Size
QTY
(R)-FTY-720 Vinylphosphonate
T713921142015-25-5
(R)-FTY-720 Vinylphosphonate is a sphingosine 1-phosphate type 1 (S1P1) receptor agonist and lacks anti-apoptotic activity.
  • $2,120
8-10 weeks
Size
QTY
(S)-FTY-720 Vinylphosphonate
T713931142015-13-1
(S)-FTY-720 Vinylphosphonate inhibits sphingosine kinase 1 and promotes its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer cells, and androgen-independent prostate cancer cells.
  • $2,120
8-10 weeks
Size
QTY
Fingolimod hydrochloride
T2539162359-56-0
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
  • $35
In Stock
Size
QTY
TargetMol | Inhibitor Sale
NBD-FTY720 phenoxy hydrochloride
T844842319882-09-0
FTY720, an immune modulator, down-regulates sphingosine-1-phosphate (S1P) receptors, enhances the activity of sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1, and inhibits cytosolic phospholipase A2 activity. Its efficacy relies on in vivo phosphorylation by sphingosine kinases, resulting in FTY720-phosphate which also down-regulates S1P receptors. NBD-FTY720, a fluorescently-labeled analog of FTY720, retains the hydroxy methyl side chain targeted for phosphorylation, suggesting potential phosphorylation in vivo.
  • Inquiry Price
8-10 weeks
Size
QTY
azido-FTY720
T37548881914-35-8
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). Down-regulation of S1P1 receptors on T and B lymphocytes by FTY720 results in defective egress of these cells from spleen, lymph nodes, and Peyer's patch. azido-FTY720 is a highly photoreactive analog of FTY720 that can be used to identify receptor binding sites for this ligand.
  • $83
35 days
Size
QTY
(S)-FTY720-phosphonate
T780911142015-10-8
FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury.
  • Inquiry Price
8-10 weeks
Size
QTY
Fingolimod-d4 HCl
TMIH-02361346604-90-7
Fingolimod-d4 HCl is a deuterated compound of Fingolimod HCl. Fingolimod HCl has a CAS number of 162359-56-0. Fingolimod, a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
  • $249
7-10 days
Size
QTY
Fingolimod
T7939162359-55-9
Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
  • $50
In Stock
Size
QTY
TargetMol | Citations Cited