luridine

Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.

Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.

5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents.

5-Bromo-2’,3’,5’-tri-O-acetyluridine is a purine nucleoside analog that is being explored to improve Alzheimer’s and Parkinson’s diseases.

L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a normal RNA isolated from Polyporaceae fungus Poria cocos (Schw.) L-Uridine has potential antiviral activity.

Trifluridine tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and tipiracil hydrochloride (TTP) in a 2:1 molar ratio.

2′-O-Methyluridine is a natural product that found in RNA such as rRNA, snRNA, snoRNA and tRNA in Archaea, Bacteria, and Eukaryota.

3-Methyluridine is a modified nucleoside of cellular RNA.

3'-O-(4,4’-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine is a useful organic compound for research related to life sciences and the catalog number is TNU1527.

Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.

5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside; Protected nucleoside with NH2/OH open; Ready for further phosphorylation.

3'-Deoxy-3'-fluoro-5-trifluoromethyluridine is a nucleoside and Reagent - Fluoro-modified nucleoside; 5-Modified pyrimidine nucleoside.

O-2,2'-Anhydro-5-methyluridine is a Nucleoside Derivative - Anhydro-nucleoside.

Nucleoside Derivatives - Fluoro-modified nucleosides; 5-Modified pyrimidine nucleosides; 3’-Deoxy nucleosides

3'-beta-C-Ethynyluridine is a Nucleoside Derivative - 3'-Modified nucleoside.

5-Pyrrolidinomethyluridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template.

Nucleoside Derivatives - 3’-Deoxy nucleosides, 5-Modified pyrimidine nucleosides; Drugs and Inhibitors; RNA chain terminator

Nucleosides - 3’-O-Methyl nucleoside

5-(Methoxycarbonyl)methyluridine (MCM5U) is a 5-modified pyrimidine nucleoside.

5-(N-Isopentenyl-N-trifluoroacetyl) aminomethyluridine is a nucleoside derivative, specifically a 5-modified pyrimidine nucleoside and an amino nucleoside [Chemical Compound].

Nucleoside Derivatives - 4-Deoxy pyrimidine nucleosides; 3’-Modified nucleosides

N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine, a uridine analog, exhibits potential for antiepileptic effects and holds promise for research into anticonvulsant and anxiolytic activities, as well as the development of novel antihypertensive agents [1].

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Amino nucleosides; 2’-Modified nucleosides

Nucleoside Derivatives - Halo-nucleosides, 5’-Modified nucleosides, 2’-Modified nucleosides

Nucleoside - 3’-O-methylnucleoside

Nucleoside Derivatives - 2’-Modified nucleosides, 5-Modified pyrimidine nucleosides

Nucleoside Derivatives - 3’-Modified nucleosides, Fluoro-modified nucleosides, N-Methylated/ alkylated nucleosides

2'-C-Methyl-5-methyluridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. 1.Jao, C.Y., and Salic, A.Exploring RNA transcription and turnover in vivo by using click chemistryProc. Natl. Acad. Sci. USA105(41)15779-15784(2008)

Nucleoside Derivatives - Azido-nucleosides, 5-Modified pyrimidine nucleosides, 3’-Modified nucleosides; Fluoro-modified nucleosides

2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl)-propyluridine [catalog number: TNU0767] is a valuable organic compound for life sciences research.

2'-beta-C-Ethynyluridine is a Nucleoside Derivative - 2'-Modified nucleoside.

3',5'-Di-O-acetyl-5-bromo-2'-O-methyluridine is a Halo-nucleoside; 2'-O-Methyl nucleoside.

5'-O-(4,4-Dimethoxytrityl)-3'-deoxy-5-methyluridine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open; 3'-Deoxy nucleoside.

Nucleoside Derivatives - 5’-Modified nucleosides, Didehydro-nucleosides, 2’-Modified nucleosides

Nucleoside Derivatives - 5’-Modified nucleosides, Halo-nucleosides, 2’-Modified nucleosides

Nucleoside Derivatives - Amino-nucleosides, 2’-Modified nucleosides, 5-Modified pyrimidine nucleosides

4'-a-C-Methyluridine is a Nucleoside Derivative - 4'-Modified nucleoside.

3'-beta-C-Methyl-5-trifluoromethyluridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.

5'-Azido-5'-deoxy-2'-O-(2-methoxyethyl)-5-methyluridine is a Nucleoside Derivative - 5'-Modified nucleoside; Azido-nucleoside; 2'-Modified nucleoside.

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-methyluridine is a nucleoside and Reagent - Fluoro-modified nucleoside; 5-Modified pyrimidine nucleoside.

5-N-Boc-aminomethyluridine is a 5-modified pyrimidine nucleoside and an amino nucleoside derivative.

Nucleoside Derivatives - Fluoro-modified nucleosides; 4’-Modified nucleosides

Nucleoside Derivatives - 5’-Modified nucleosides; 5-Modified pyrimidine nucleosides

N3-[3-(tert-Butoxycarbonyl)amino]propyluridine is a nucleoside derivative classified under other modified nucleosides.

5'-(4,4'-Dimethoxytrityl)-5-methyluridine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open.

Nucleoside Derivatives – 5’-Modified nucleosides, 2’-Modified nucleosides, Didehydro-nucleosides

Nucleoside Derivatives - 5’-Modified nucleosides, Azido-nucleosides, 2’-Modified nucleosides

Nucleoside Derivatives - 4’-Modified nucleosides, 5-Modified pyrimidine nucleosides

3'-b-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine is a Nucleoside Derivative - Amino-nucleoside, Xylo-nucleoside, 2',3'-Didexoy nucleoside, 3'-Modified nucleoside; Protected nucleoside with NH2/OH group.