mutagen

Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and carcinogenic activity.

Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.

N-Nitroso-N-methylurea is a nitrosourea compound with alkylating, carcinogenic and mutagenic properties. It targets a variety of animal organs, causes various cancers and degenerative diseases, and can be used in diazomethane synthesis.

Aristolochic acid B (Aristolochic Acid II) is a natural product from the Aristolochaceae taxon and is one of the main components of aristolochic acid. Aristolochic acid is a mutagen and carcinogen, and Aristolochic acid B (Aristolochic Acid II) can show a greater carcinogenic risk in vivo than Aristolochic acid I.

Acrylamide-2,3,3-d3 is a deuterated compound of Acrylamide. Acrylamide has a CAS number of 79-06-1. Acrylamide is a member of the class of acrylamides. It has a role as a carcinogenic agent, a neurotoxin, a mutagen, an alkylating agent and a Maillard reaction product

Aziridyl benzoquinone, an antineoplastic agent, has been studied as a mutagen and as a carcinogenic agent.

Djalonensone (Alternariol monomethyl ether), an Alternaria toxin, is a strong mutagen in Escherichia coli strain ND-160. Alternariol monomethyl ether has genotoxic properties, it can cause oxidative DNA damage. It also possesses cytotoxic and immunosuppressive properties.

Dimethylnitrosamine (NDMA), a potent hepatotoxin, carcinogen, and mutagen, induces liver tumors [1] [2].

CP 67015 has an inhibitory effect on the function of topoisomerase, and is a direct mutagen in mammalian cells, which has effects on gene and chromosome levels.

DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, DL-Glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. DL-Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. DL-Glyceraldehyde modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). DL-Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.

4-OHE ((E)-4-Oxo-2-hexenal), a mutagen, originates from the peroxidation of omega-3 fats and exhibits antibacterial activity .