narcotic

Deracoxib (SC 46) is a non-steroidal, non-narcotic anti-inflammatory drug. It is also a selective cyclooxygenase-2 inhibitor, and IC50 Value: 70 to 150 μM(inhibition of 3 osteosarcoma cell lines).

Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.

Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Glafenine (Glafenin), a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of various origins.

Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.

W-2429 (NSC294836) is a non-narcotic analgesic that may be used in the study of neurological disorders.

Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.

20681-S has narcotic antagonistic properties and antinociceptive.

Brifentanil hydrochloride is a potent narcotic analgesic.

Methylnaltrexone is a narcotic antagonists.

Ruzadolane (formerly known as UP 26-91) is a 5-hydroxytryptamine receptor antagonist developed as a non-narcotic central analgesic for the treatment of anxiety disorders and pain.

Ciramadol (WY 15705) is a potent, orally active analgesic with both narcotic agonist and antagonist properties, beneficial for postoperative pain treatment research.

FK 33-824 ,with similar actions to those of methionine enkephalin(ENKEPHALIN, METHIONINE),is a stable synthetic analog of that. Its effects can be reversed by narcotic antagonists such as naloxone.

Cyclazocine is an analgesic with mixed narcotic agonist-antagonist properties.

Oxpheneridine is a mu opioid receptor agonist that possesses the spasmolytic activity and acts as a narcotic analgesic.

DA 5018 is a capsaicin derivative and is also a new non-narcotic analgesic. It has an antipruritic effect.

Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.

Lofexidine, a selective α2-receptor agonist, reduces narcotic withdrawal symptoms.

Methylnaltrexone is a narcotic antagonist.

MR 2266 is a narcotic antagonist.

LY 99335 is a narcotic antagonist in the class of phenylpiperidine.

LY 88329 is a narcotic antagonist in the class of phenylpiperidine.

Tipepidine is a non-narcotic antitussive with an antidepressant-like effect. Tipepidine reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK) ) (IC 50 = 7.0 μM) and subsequently activates VTA dopamine neurons.

Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing guaifenesin have been used as expectorants in the treatment of the common cold and chronic bronchitis.