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  • Apoptosis
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  • Caspase
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  • Ferroptosis
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  • Indoleamine 2,3-Dioxygenase (IDO)
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Results for "

necrostatin

" in TargetMol Product Catalog
  • Inhibitor Products
    12
    TargetMol | Activity
Necrostatin-1
T18474311-88-0
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.
  • $30
In Stock
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QTY
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TargetMol | Citations Cited
Necrostatin 2 racemate
T7504852391-15-2
Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.
  • $59
In Stock
Size
QTY
TargetMol | Citations Cited
Necrostatin-34
T9095375835-43-1
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
  • $80
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Necrostatin-1 (inactive control)
T8472764419-92-7
Necrostatin-1 (Nec-1) (inactive control), an inactive analog of Necrostatin-1, functions as a potent inhibitor of necroptosis [1].
  • Inquiry Price
Size
QTY
Necrostatin 2 S enantiomer
T12203852391-20-9
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2
  • $119
5 days
Size
QTY
Necrostatin-5
T37558337349-54-9
Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM.
  • $38
In Stock
Size
QTY
Cl-Necrostatin-1
T68520862377-51-3
Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.
  • $123
35 days
Size
QTY
Necrostatin 2
T12203L852391-19-6
Necrostatin 2 is an effective necroptosis inhibitor. Necrostatin 2 is also a RIPK1 inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM.
  • $78
5 days
Size
QTY
Necrostatin-7
T25859351062-08-3
Necrostatin-7 (Necrostatin 7) is an inhibitor of necrotic apoptosis with cardioprotective effects, inhibits RANK-NFATc1 signaling, and attenuates macrophage differentiation into osteoblasts.
  • $39
In Stock
Size
QTY
Necroptosis-IN-1
T93051391980-92-9In house
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
  • $96
In Stock
Size
QTY
CIL62
T8468117593-36-9
CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].
  • $80
In Stock
Size
QTY
Nec-3a
T735211504558-72-8
Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM. This compound successfully impedes the autophosphorylation activity within the RIP1 kinase domain.
  • $1,520
6-8 weeks
Size
QTY