pectoris

Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.

Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.

Lefradafiban（BIBU-104） is an oral platelet glycoprotein IIb/IIIa receptor antagonist for the study of angina pectoris and acute coronary syndromes.

Brefonalol HCl is an ADRA antagonist used in the treatment of neurological disorders and cardiovascular diseases and can be used in the study of angina pectoris, arrhythmias and hypertension.

m-Nisoldipine (3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) is a dihydropyridine calcium channel blocker, a derivative of nisoldipine, that blocks L-type calcium channels in the heart and smooth muscle cells for the treatment of hypertension and angina pectoris.

Alinidine is an HCN channel blocker with antiarrhythmic effects and can be used for the study of angina pectoris.

Elgodipine significantly reduced the incidence and severity of exercise-induced angina pectoris systemically and was able to inhibit vascular smooth muscle proliferation through a mechanism independent of the expression of the transcription factors c-fos and c-jun. The Elgodipine-induced inhibition was voltage-dependent. Elgodipine is a potential compound for the treatment of angina pectoris.

Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.

Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases, and can be used in the study of angina pectoris.

Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias, and angina research.

Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.

Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.

Palonidipine HCl is a calcium channel antagonist potentially for the treatment of angina pectoris and hypertension.

Prenylamine lactate is a drug formerly used in the treatment of angina pectoris. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity.

Diacetolol is the major metabolite of acebutolol, a selective beta blockers used to treat hypertension, angina pectoris and arrhythmia.

Viscumneoside III, a dihydroflavone O-glycoside, is a potent tyrosinase inhibitor with an IC50 of 0.5 mM, and has anti-angina pectoris properties.

Lincydomine is a smooth muscle relaxant, beneficial to the treatment of unstable angina pectoris, but also can open the respiratory tract of humans and guinea pigs.

Etafenone is a vasodilator for the therapy of anigna pectoris.

NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure.

Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.

KF 14124 exhibits potent anti-ischemic activity in a lysine-vasopressin-induced angina pectoris model (rats).

SL-870495, a calcium channel antagonist, is used potentially for the treatment of angina pectoris.

Dopropidil is a new anti-angina pectoris calcium regulator, which has intracellular calcium antagonist activity and anti-ischemic effects in various predicted animal models.

Tedisamil is a blocker of K+ currents in cardiac tissues, exerts bradycardic effects. It is an antiarrhythmic drug with predominantly class III activity. It has shown clinical efficacy in angina pectoris.

Acebutolol D7 is a deuterium-labeled Acebutolol. Acebutolol is a selective antagonist of the β1 adrenergic receptor used in the treatment of angina pectoris, hypertension, and cardiac arrhythmias.

Toliprolol is an adrenergic receptor antagonist with some stimulant action; it has been proposed for angina pectoris.

Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 = 4.4 µM). It decreases mean blood pressure, coronary resistance, and heart rate, as well as increases coronary sinus outflow, in dogs when administered intravenously at a dose of 1 mg/kg. Nicorandil increases survival and decreases infarct size in a rabbit model of myocardial ischemia-reperfusion injury induced by left coronary artery occlusion. Formulations containing nicorandil have been used in the treatment of angina pectoris.

Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. Nadolol competitively blocks beta-1 adrenergic receptors located in the heart and vascular smooth muscle, inhibiting the activities of the catechola

Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor of the hydrazine chemical class. It was also used in the treatment of angina pectoris and schizophrenia.

Celiprolol-d9 Hydrochloride is a deuterated compound of Celiprolol Hydrochloride. Celiprolol Hydrochloride has a CAS number of 57470-78-7. Celiprolol hydrochloride is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.

Dopropidil, a calcium channel antagonist, is used potentially for the treatment of arrhymia and angina pectoris.

Palonidipine is an antagonist of calcium, is potential for the therapy of angina-pectoris and hypertension.

Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].

Isorauhimbine is an alkaloid derived from R. serpentina with anticancer, anti-inflammatory and antimicrobial activities and is used in the treatment of cardiovascular diseases such as hypertension, arrhythmia and angina pectoris.

Atenolol (Tenormin) is a selective β1 receptor antagonist.