pyrazole

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent.

1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid (1,3,5-trimethylpyrazole-4-carboxylic acid) is a marine derived natural products found in Cinachyrella sp.

(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide is a cannabinoid receptor antagonist/inverse agonist.

1H-Pyrazole-3-carboxylic acid is an important intermediate in the synthesis of various pharmaceuticals and agricultural chemicals and is also used in the synthesis of compounds such as pyrazolones, pyrazole amides, and pyrazolines.

XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1].

4-Methyl-1H-pyrazole hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T67682.

Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression.

3-Amino-1H-pyrazole-4-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67506 and the CAS number is 5334-31-6.

Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).

tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66374 and the CAS number is 1280210-79-8.

3-Methyl-5-phenyl-1H-pyrazole is a useful organic compound for research related to life sciences. The catalog number is T67598 and the CAS number is 3347-62-4.

Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.

1H-Pyrazole, 4,5-dihydro-1,3,5-triphenyl- is a bioactive chemical.

4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67079 and the CAS number is 139756-02-8.

1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T65742 and the CAS number is 139756-01-7.

3-(p-Tolyl)-1H-pyrazole is a useful organic compound for research related to life sciences. The catalog number is T67474 and the CAS number is 59843-75-3.

1H-Pyrazole-3,5-dicarboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66472 and the CAS number is 3112-31-0.

1H-Pyrazole-1-carboximidamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67134 and the CAS number is 4023-02-3.

1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65741 and the CAS number is 139755-99-0.

1-methyl-1H-pyrazole-4-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67140 and the CAS number is 113100-53-1.

1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.

3-Amino-1H-pyrazole-4-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T66363 and the CAS number is 16617-46-2.

1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67141 and the CAS number is 139756-00-6.

4-Amino-1-methyl-3-(2-methylpropyl)-1H-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T64521 and the CAS number is 268204-00-8.

1,5-diphenylpyrazole-3-carboxylic acid (1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL-) is a plant-physiologically tolerable salt radical or any desired ester radical.

1,3-Dimethylpyrazole (2,5-Dimethylpyrazole) is a bioactive compound isolated from Moso Bamboo Root.

3-Amino-4-pyrazolecarboxamide hemisulfate is a useful organic compound for research related to life sciences. The catalog number is T65014 and the CAS number is 27511-79-1.

Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.

Pyrazinoic acid (Pyrazinecarboxylic acid) is the intermediate of pyrazole thiamethoxam sulfur.

Zometapine (CI 716) is an antidepressant compound that is a derivative of pyrazole and diazepine.

ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through inhibition of the NF-κB signaling pathway, in the regulation of antioxidant response through activation of the Nrf2 signaling pathway, and in the regulation of cell survival and proliferation through inhibition of the Akt signaling pathway.

5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile is a compound used as a molecular structural unit and is considered to be an inhibitor of enzymes such as COX-2, 5-LOX, etc., and possesses a wide range of biochemical and physiological effects including antitumor activity, anti-inflammatory effects and antioxidant activity.

ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate, also known as EAPT, is a potent and selective PDE4 inhibitor that regulates intracellular cyclic adenosine monophosphate (cAMP) levels. It has been used in a variety of scientific applications, including the study of cAMP-mediated signaling pathways, and has potential as a therapeutic agent for the treatment of inflammatory and immune-related diseases.

4-Carboxypyrazole is an endogenous metabolite.

Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM.

4-Hydroxymethylpyrazole is a natural product for research related to life sciences. The catalog number is T66965 and the CAS number is 25222-43-9.

Ethyl 5-Propylpyrazole-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66268 and the CAS number is 92945-27-2.

LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).

Pentanochlor can be used in agricultural use and biological study of herbicide composition containing a pyrazolyl pyrazole derivative. The impairment of mobility and development in freshwater snails (Physa fontinalis and Lymnaea stagnalis) caused by herbi

1-Methyl-1H-pyrazol-3-amine is a pyrazole compound. It has been used in the synthesis of various compounds such as drugs, dyes and polymers. It is also an important intermediate in the synthesis of certain drugs. It has also been used in the development of new drugs and in the study of enzyme inhibitors and receptor modulators.

JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endo

PK7088, a pyrazole-based peptide, selectively reactivates mutant p53 to a conformation with wild-type characteristics, demonstrating anticancer activity in oncological studies [1].

Bucloxic acid is an anti-inflammatory pyrazole derivative used in the treatment of chronic glomerular nephropathies.

Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulate

Feniralstat is a pyrazole derivative, a potent inhibitor of kallikrein, which inhibits human plasma kinase (pKal) (IC50: 6.7 nM).Feniralstat does not inhibit human KLK1, human FXIa and human factor Xlla (IC50 >40 μM).

yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)

Muzolimine is pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.

Betazole (Ametazole), a pyrazole analogue of histamine, functions as an orally active agonist of the histamine H2 receptor. It effectively induces gastric acid secretion and significantly elevates common bile duct pressure immediately. Utilized as a diagnostic tool, Betazole serves under the name histalog to assess gastric acid secretory capacity.

Bucloxic acid calcium salt is a pyrazole derivative, the calcium salt of Bucloxic acid. It is an anti-inflammatory drug with analgesic and antipyretic properties. It is also used in the study of chronic glomerulonephropathy.

Atinvicitinib, a pyrazole compound, exhibits promise for investigating atopic dermatitis.