vinca

Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.

Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, which is a derivative of Vincamine with vasodilating activity.

14,15-Didehydrovincamenine is a natural product for research related to life sciences. The catalog number is TN2620 and the CAS number is 112219-48-4.

16-O-Methyl-14,15-didehydroisovincanol is a natural product for research related to life sciences. The catalog number is TN2649 and the CAS number is 112237-71-5.

16,17-Dihydroapovincamine is a natural product for research related to life sciences. The catalog number is TN2642 and the CAS number is 57130-30-0.

19-Hydroxypseudovincadifformine is a useful organic compound for research related to life sciences and the catalog number is T125260.

Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.

Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.

Halichondrin B, sourced from the sponge Halichondria okadai, serves as a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin, with an IC 50 for tubulin polymerization ranging from 1.2-1.4 μM, and exhibits anti-tumor activity [1].

Vinburnine (Eburnalritardo) is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine.

Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.

Kopsinine, an indole alkaloid, is derived from the flowers of the periwinkle plant (Vinca spp.) [1].

Vinorelbine (KW-2307 base) is a semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents the formation of the mitotic spindle, resulting in the arrest of tumor cell growth in metaphase.