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West Nile Virus (WNV) (lineage 1, strain NY99) E Envelope Protein (His) is expressed in yeast with His tag. The predicted molecular weight is 12.9 kDa and the accession number is ABA62343.1.

West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E Envelope Protein (His) is expressed in yeast with His tag. The predicted molecular weight is 12.9 kDa and the accession number is AED99787.1.

West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is YP_001527881.1.

Influenza A H15N2 (A Australian shelduck Western Australia 1756 1983) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q2FCC6.

Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell. Produces the wrapped form of virus that is required for cell-to-cell spread. Acts as a lipase with broad specificity including phospholipase C, phospholipase A, and triacylglycerol lipase activities. Vaccinia virus (strain Western Reserve) OPG057 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.2 kDa and the accession number is P04021.

Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation). Vaccinia virus (strain Western Reserve) OPG094 Protein (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 37.8 kDa and the accession number is P07611.

Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). Vaccinia virus (strain Western Reserve) OPG190 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is Q01227.

Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response. Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.9 kDa and the accession number is P26670.

Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is Q01227.

Structural protein involved in the envelopment of mature virion (MV) to form the wrapped virion (WV). The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion (MV) movement within the infected cell. May play an indirect role in MV-cell fusion. Vaccinia virus (strain Western Reserve) OPG154 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.6 kDa and the accession number is P11258.

Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell. Vaccinia virus (strain Western Reserve) L1 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.8 kDa and the accession number is P07612.

Coordinates the incorporation of A36 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles. Vaccinia virus (strain Western Reserve) OPG161 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.2 kDa and the accession number is P68617.

Influenza A H15N2 (A Australian shelduck Western Australia 1756 1983) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q2FCC6.

Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2 PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2 PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 26.6 kDa and the accession number is P18378.

Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell. Vaccinia virus (strain Western Reserve) L1 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P07612.

Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2 PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2 PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain Western Reserve) K3 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.6 kDa and the accession number is P18378.

Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon-inducible transmembrane protein family members, IFITM1, 2, and 3, are IEGs required for inhibition of influenza A virus, dengue virus, and West Nile virus replication in vitro. IFITM3 is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. It is both necessary and sufficient for preventing the emergence of viral genomes from the endosomal pathway. Viral pseudo particles were inhibited from transferring their contents into the host cell cytosol by IFN, and IFITM3 was required and sufficient for this action. IFITM3 overexpression is sufficient for this phenotype. Moreover, IFITM3 partially resides in late endosomal and lysosomal structures, placing it in the path of invading viruses.