GHSR

Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone". The role of GHS-R is thought to be in regulating energy homeostasis and body weight. In the brain, they are most highly expressed in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus. GSH-Rs are also expressed in other areas of the brain, including the ventral tegmental area, hippocampus, and substantia nigra. Outside the central nervous system, too, GSH-Rs are also found in the liver, in skeletal muscle, and even in the heart.

Cat. No.	Product name	CAS No.	Purity
T12216L	NF-56-EJ40 hydrochloride	2728500-80-7	98%
T12216L	NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almo...
T11560	HGPR91 antagonist 1	1314796-00-3	98%
T11560	hGPR91 antagonist 1 is a potent and selective hGPR91 antagonist (IC50: 7 μM).
T10319	Anamorelin	249921-19-5	98%
T10319	Anamorelin is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
T16508	PF-5190457	1334782-79-4	98%
T16508	PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36).
T23543	YIL 781	875258-85-8	98%
T23543	YIL 781 is a selective ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM), showing a weak affinity for kinesin receptors (K = 6 μM). YIL 781 improves glucose hom...
TP1155L	Human growth hormone-releasing factor acetate		98%
TP1155L	Human growth hormone-releasing factor acetate is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on c...
TP2279L	Obestatin (rat) acetate		98%
TP2279L	Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin (rat) acetate has anti-inflammatory, anti-myocardial infarcti...
T4648	TC-G-1008	1621175-65-2	98%
T4648	TC-G-1008 is a GPR39 (zinc receptor) agonist (EC50 values are 0.4 and 0.8 nM for rat and human receptors respectively).
T11719	JMV 2959 hydrochloride (925238-89-7 free base)	2448414-54-6	98%
T11719	JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
TP2328L	CJC-1295 acetate(863288-34-0 free base)	TP2328L	98%
TP2328L	CJC-1295 acetate is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone se...
T7112	Ibutamoren Mesylate	159752-10-0	98%
T7112	Ibutamoren Mesylate is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
T17103	TM-N1324	1144477-35-9	98%
T17103	TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively...
T7225	AnaMorelin hydrochloride	861998-00-7	98%
T7225	Anamorelin hydrochloride is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).
TP2236L	Cortistatin-8 acetate	TP2236L	98%
TP2236L	Cortistatin-8 acetate is a corticosteroid analog, a GHS-R antagonist with inhibitory effects on the growth hormone pro-secretin receptor.Cortistatin-8 acetate is...
TQ0022	Capromorelin Tartrate	193273-69-7	98%
TQ0022	Capromorelin Tartrate is a potent, orally active growth hormone secretagogue receptor (GHSR) agonist (Ki: 7 nM for hGHS-R1a).