Gap Junction Protein

Gap junctions are a specialized intercellular connection between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulated gate between cells.One gap junction channel is composed of two connexons (or hemichannels), which connect across the intercellular space. Gap junctions are analogous to the plasmodesmata that join plant cells.

Cat. No.	Product name	CAS No.	Purity
T7732	Carbenoxolone	5697-56-3	98%
T7732	Carbenoxolone is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development ...
T11990	Meclofenamic acid	644-62-2	98%
T11990	Meclofenamic acid is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-infl...
T19335	Danegaptide Hydrochloride	943133-81-1	98%
T19335	Danegaptide Hydrochloride (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.
T16790L	Rotigaptide TFA(355151-12-1 free base)	T16790L	98%
T16790L	Rotigaptide TFA is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication an...
T5192	Gap 26	197250-15-0	98%
T5192	Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
T0992	Carbenoxolone disodium	7421-40-1	98%
T0992	Carbenoxolone disodium salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuret...
TP1563	Gap19	1507930-57-5	98%
TP1563	Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
T15711	Larazotide acetate	881851-50-9	98%
T15711	Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.
TP1333	Gap 27	198284-64-9	98%
TP1333	Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.
T0342	Carvedilol phosphate hemihydrate	610309-89-2	98%
T0342	Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intri...
T0260	Meclofenamic acid sodium	6385-02-0	98%
T0260	Meclofenamate Sodium, a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosy...
TP2110L	TAT-Gap19 acetate	TP2110L	98%
TP2110L	TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis ...