T2080 |
LCL161 |
LCL161, a SMAC mimetic, effectivity binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). |
T3981 |
Acacetin |
Acacetin is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models. |
T6007 |
Birinapant |
Birinapant is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibi...
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T6299 |
GDC-0152 |
GDC-0152 is a potent inhibitor of IAPs. |
T6428 |
BV6 |
BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. |
T6485 |
Embelin |
Embelin, isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM). |
T6763 |
AT406 |
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cI...
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TQ0029 |
ASTX660 |
ASTX660 is an orally bioavailable dual antagonist of cIAP and XIAP. |
T3299 |
AT-406 HCl |
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 a...
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T12932 |
SM-164 Hydrochloride |
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) an...
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T11651 |
Indanidine |
Indanidine is an alpha-adrenergic agonist. |
T12932L |
SM-164 |
SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP. |
TN5263 |
Xanthohumol |
Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic ef...
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