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MyD88

MyD88 (Myeloid differentiation primary response gene 88) is a protein that is encoded by the MYD88 gene in humans. Available evidence suggests that MYD88 is dispensable for human resistance to common viral infections and to all but a few pyogenic bacterial infections, demonstrating a major difference between mouse and human immune responses. MyD88 is an essential adaptor protein in the IL-1R1 signaling pathway. MyD88 may define a family of signal transduction molecules with an ancestral function in the activation of the immune system. MyD88 functions as a pure adaptor linking the IL-1R1 to downstream IRAK kinases. Mutation in MYD88 at position 265 leading to a change from leucine to proline have been identified in many human lymphomas including ABC subtype of Diffuse Large B-cell Lymphoma and Waldenstrom's Macroglobulinemia.
Cat No. product name
T9765 TJ-M2010-5 TJ-M2010-5 是一种 MyD88 抑制剂,可与 TIR 结构域结合以干扰其同源二聚化并抑制 MyD88 信号传导。 TJ-M2010-5 可用于心肌缺血/再灌注损伤研究。
T3898 Schaftoside Schaftoside has antioxidant and anticancer activity.
T13932 TLR1 TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
T13063 T6167923 T6167923 is a potent and selective MyD88-dependent signaling pathways inhibitor.
TJ-M2010-5
T9765
Schaftoside
T3898
Schaftoside has antioxidant and anticancer activity.
TLR1
T13932
TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
T6167923
T13063
T6167923 is a potent and selective MyD88-dependent signaling pathways inhibitor.