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Myosin

Myosins are a superfamily of motor proteins best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility.
Cat. No. Product name CAS No. Purity Chemical Structure
T72060 Myosin V-IN-1 1259177-59-7 98%
Myosin V-IN-1 is a potent and selective inhibitor of Myosin V with a Ki value of 6 μM.Myosin V-IN-1 inhibits actin V and slows down actin-activated myosin V ATPa...
T7144 BTS 1576-37-0 98%
BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
T7134 Mavacamten 1642288-47-8 98%
MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
T67951 JB061 98%
JB061 is a nonmuscle myosin inhibitor with IC 50 s of 4.4 μM ( Cardiac muscle myosin ), 9.1 μM ( Skeletal muscle myosin ), and >100 μM ( Smooth muscle myosin II ...
T72023 JB002 30408-07-2 98%
JB002 is a myosin II inhibitor, with an IC 50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic ...
T24214 Phenamacril 39491-78-6 98%
JS399-19 is a specific Fusarium myosin I inhibitor that acts as a fungicide.
T67952 JB062 2417988-00-0 98%
JB062 is a nonmuscle myosin inhibitor with IC 50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin , Cardiac muscle myosin , and Smooth muscle myosin II...
T6038 (-)-Blebbistatin 856925-71-8 98%
(-)-Blebbistatin is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
T16104 ML-9 105637-50-1 98%
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits...
T3050 ML-7 hydrochloride 110448-33-4 98%
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-musc...
T2006 Omecamtiv mecarbil 873697-71-3 98%
Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, an...
T7648 HA-100 84468-24-6 98%
HA-100 is an inhibitor of protein kinase
T20792 W-7 hydrochloride 61714-27-0 98%
W-7 HCl, a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has...
T15050 Danicamtiv 1970972-74-7 98%
Danicamtiv is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves ...
T12360 Para-Nitroblebbistatin 1621326-32-6 98%
para-Nitroblebbistatin is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in the study of the spec...
T21550 Blebbistatin 674289-55-5 98%
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound he...
Myosin V-IN-1
T72060
Myosin V-IN-1 is a potent and selective inhibitor of Myosin V with a Ki value of 6 μM.Myosin V-IN-1 inhibits actin V and slows down actin-activated myosin V ATPa...
BTS
T7144
BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
Mavacamten
T7134
MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
JB061
T67951
JB061 is a nonmuscle myosin inhibitor with IC 50 s of 4.4 μM ( Cardiac muscle myosin ), 9.1 μM ( Skeletal muscle myosin ), and >100 μM ( Smooth muscle myosin II ...
JB002
T72023
JB002 is a myosin II inhibitor, with an IC 50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic ...
Phenamacril
T24214
JS399-19 is a specific Fusarium myosin I inhibitor that acts as a fungicide.
JB062
T67952
JB062 is a nonmuscle myosin inhibitor with IC 50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin , Cardiac muscle myosin , and Smooth muscle myosin II...
(-)-Blebbistatin
T6038
(-)-Blebbistatin is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
ML-9
T16104
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits...
ML-7 hydrochloride
T3050
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-musc...
Omecamtiv mecarbil
T2006
Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, an...
HA-100
T7648
HA-100 is an inhibitor of protein kinase
W-7 hydrochloride
T20792
W-7 HCl, a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has...
Danicamtiv
T15050
Danicamtiv is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves ...
para-Nitroblebbistatin
T12360
para-Nitroblebbistatin is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in the study of the spec...
Blebbistatin
T21550
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound he...