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Prolyl Endopeptidase (PREP)

Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene. Prolyl endopeptidase is a large cytosolic enzyme that belongs to a distinct class of serine peptidases. It was first described in the cytosol of the rabbit brain as an oligopeptidase, which degrades the nonapeptide bradykinin at the Pro-Phe bond. The enzyme is involved in the maturation and degradation of peptide hormones and neuropeptides.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78619 Z-Pro-Pro-CHO 108708-25-4 98%
Z-Pro-Pro-CHO
Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01 μM...
T80106 Z-Pro-Pro-aldehyde-dimethyl acetal 170116-63-9 98%
Z-Pro-Pro-aldehyde-dimethyl acetal
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease w...
TN4442 Linderene acetate 26146-28-1 99.75%
Linderene acetate
Linderene acetate is a competitive inhibitor against Prolyl endopeptidase.
T35233 Y-29794 Tosylate 143984-17-2 99.10%
Y-29794 Tosylate
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.
Z-Pro-Pro-CHO
T78619
Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01 μM...
Z-Pro-Pro-aldehyde-dimethyl acetal
T80106
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease w...
Linderene acetate
TN4442
Linderene acetate is a competitive inhibitor against Prolyl endopeptidase.
Y-29794 Tosylate
T35233
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.
TargetMol