Angustifoline is a natural alkaloid isolated from Lupinus angustifolius L., exhibiting antimicrobial and anticancer properties. It inhibits the growth of various bacteria(S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis) and induces autophagy and apoptosis in human colon cancer cells.

Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokines and blocking of IFN-β STAT1 pathw

Lupanine ((+)-Lupanine), a naturally occurring quinolizidine alkaloid, potently affinity and activates nicotinic acetylcholine receptor (nAChR) (Ki=500 nM), and shows significant neuroprotection against soluble amyloid β-oligomers (SO-Aβ) toxicity in cellular models in association with the anti-apoptotic PI3K Akt Bcl-2 signaling pathway with anti-Alzheimer's disease potential. Improves glucose homeostasis by affecting KATP channels and enhancing insulin secretion with therapeutic potential for type 2 diabetes.

Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.

Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management.

2'-Hydroxygenistein is a naturally occurring flavonoid with a wide range of antioxidant, anti-inflammatory, anticancer, and anti-endometrial hyperplasia potentials.2'-Hydroxygenistein is a inhibitor of a variety of enzymes, including indole-3-acetic acid oxidase, α-glucosidase, β-glucuronidase, and lysozyme.

Topazolin has weak fungitoxic activity, it displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug mL, it also shows in vitro free radical scavenging activities with IC50 values in the range of 0.18-0.56 mg mL.

6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.

Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug disc. Sophoraisoflavone A shows inhibitory effects on copper-induced prot