asparagine

L-Asparagine (Asparamide) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase.

DL-Asparagine is a natural product for research related to life sciences. The catalog number is TN3877 and the CAS number is 3130-87-8.

(S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine), also known as acasn, is an endogenous metabolite.

D-Asparagine (H-D-Asn-OH) serves as a nitrogen source for yeast strains and acts as a competitive inhibitor of L-Asparagine hydrolysis with a Ki of 0.24 mM.

L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function.

2,4-Dihydroxyphenylacetyl-L-asparagine is a natural product for research related to life sciences. The catalog number is T37949 and the CAS number is 111872-98-1.

L-Aspartic acid (Aspatofort) is a non-essential amino acid in humans, L-Aspartic acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles. Asparagine, arginine, lysine, methionine, isoleucine, and some nucleotides are synthesized from aspartic acid. L-Aspartic acid also serves as a neurotransmitter.

Aminomalonic acid is an amino endogenous metabolite that acts as a potent inhibitor of L-asparagine synthetase from Leukemia 5178Y AR and mouse pancreas in vitro (Leukemia 5178Y AR: Ki= 0.0023 M, mouse pancreas: Ki= 0.0015 M). It has the potential to be used as a biomarker to distinguish between different stages of melanoma metastasis.

Bisabosqual A is a potent asparagine synthetase (ASNS) inhibitor with an IC 50 of 10.7 μM, capable of covalently modifying the K556 site of the ASNS protein. It induces oxidative stress and apoptosis, while inhibiting autophagy, cell migration, and epithelial-mesenchymal transition (EMT), thereby slowing cancer cell development [1].

Aminomalonic acid is an amino endogenous metabolite that acts as a potent inhibitor of L-asparagine synthetase from Leukemia 5178Y AR and mouse pancreas in vitro (Leukemia 5178Y AR: Ki= 0.0023 M, mouse pancreas: Ki= 0.0015 M). It has the potential to be used as a biomarker to distinguish between different stages of melanoma metastasis.