carbamoyl

(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin . (-)-Sitagliptin carbamoyl glucuronide is formed by N-carbamoyl glucuronidation and has been found in rat and dog plasma following administration of (-)-sitagliptin.

2-Carbamoyl-3-hydroxy-1,4-naphthoquinone is a natural product for research related to life sciences. The catalog number is TN5790 and the CAS number is 103646-20-4.

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a polyethylene glycol (PEG) derivative that serves as a linker for proteolysis targeting chimeras (PROTACs) synthesis [1].

N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is an intermediary product in pyrimidine biosynthesis.

(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66476 and the CAS number is 623950-02-7.

m-((3-Chloro-4-(3-(2,4,6-triamino-5-pyrimidinyl)propoxy)phenyl)carbamoyl)benzenesulfonyl fluoride monoethanesulfonate can be used in related research in the field of life sciences. Its product number is T33123 and CAS number is 22478-95-1.

m-((3-Chloro-4-(3-(2,4,6-triamino-5-pyrimidinyl)propoxy)phenyl)carbamoyl)benzenesulfonyl fluoride is a bioactive chemical.

[(2,6-Dimethylphenyl)Carbamoyl]Formic acid is a useful organic compound for research related to life sciences. The catalog number is T66191 and the CAS number is 2903-48-2.

CX08005 is a protein tyrosine phosphatase 1B inhibitor. CX08005 reduces hepatic lipid accumulation and microcirculatory impairment associated with non-alcoholic fatty liver disease.

Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.

TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.

Bromisoval (Isobromyl) is a mild hypnotic and sedative with potential toxicity.

Ethyl 2-carbamoyloxybenzoate, abbreviated as ECXB, is a compound used as a molecular structural unit. It is a synthetic derivative of benzoyloxybenzoic acid and has been used in the synthesis of drugs, the study of biochemical and physiological effects of compounds, the study of drug metabolism, and the study of the effects of drugs on the body.

Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.

Lenvatinib impurity 10 is a useful organic compound for research related to life sciences and the catalog number is T64460.

S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) is an isothiocyanate derivative, functioning as an active metabolite of sulforaphane, a class I and II histone deacetylase (HDAC) inhibitor, and anticancer agent. This compound is generated from sulforaphane through intermediates - DL-sulforaphane glutathione and sulforaphane cysteinylglycine - via the mercapturic acid pathway enzymes. At a concentration of 20 µM, SFN-Cys diminishes invasion and migration of U87MG and U373 MG glioblastoma cells as observed in wound healing and chamber assays. Furthermore, at 45 µM, it significantly lowers the expression of α-tubulin, βIII-tubulin, stathmin 1, and X-linked inhibitor of apoptosis (XIAP), and also reduces cell density in paclitaxel-resistant A549 lung cancer cells (A549/T). Additionally, when used at 30 µM, SFN-Cys prompts apoptosis and cell cycle arrest at the G2/M phase in U87MG and U373 MG cells.

S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) is an anticarcinogenic agent. S-(N-PhenethylthiocarbaMoyl)-L-cysteine shows antileukemic activity which inhibits DNA synthesis in HL60 cells [1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is an inhibitor of P450 [2].

N2-acetyl-O6-(diphenylcarbamoyl)guanine is a useful organic compound for research related to life sciences. The catalog number is TNU0794 and the CAS number is 112 233-74-6.

Bromoacetamido-PEG9-ethylcarbamoyl-C4-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, used for synthesizing PROTACs[1].

Valeranilide, 2-chloro-3'-hydroxy-, methylcarbamate (ester) is a bioactive chemical.

Methyl 2-Carbamoylbenzoate is a useful organic compound for research related to life sciences and the catalog number is T66792.

Bromoacetamido-PEG9-ethylcarbamoyl-C8-Boc represents a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

1-(Phenylcarbamoyl)cyclopropanecarboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T64409 and the CAS number is 145591-80-6.

Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate is a useful organic compound for research related to life sciences. The catalog number is T66530 and the CAS number is 1332524-01-2.

Descarbamoyl cefuroxime is also an intermediate in the synthesis of cephalosporin antibiotics. Decarbamyl cefuroxime is a degradation product of cefuroxime.

Bromoacetamido-PEG9-ethylcarbamoyl-C12-Boc is a polyethylene glycol (PEG) derived linker employed for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalate is a useful organic compound for research related to life sciences. The catalog number is T66624 and the CAS number is 1210348-34-7.

5-Carbamoylmethyl uridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Naturally modified Ribo-nucleoside.

(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate is a useful organic compound for research related to life sciences. The catalog number is T66068 and the CAS number is 134395-00-9.

2-Acetylamino-1-{3’-O-[(4,4’-dimethoxy triphenyl)methyl]-a-L-threo furanosyl}-6-(N,N-diphenylcarbamoyloxy)-9H-purine is a nucleoside analog and has a wide range of applications in life science related research.

2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66529 and the CAS number is 1289942-66-0.

(2S,4S)-4-Nitrobenzyl 2-(dimethylcarbamoyl)-4-mercaptopyrrolidine-1-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66293 and the CAS number is 96034-64-9.

Ammonium, (m-(N-methylcarbamoylmethoxy)phenyl)trimethyl-, methylsulfate is a bioactive chemical.

DOTA-LM3 is a somatostatin receptor (SSTR) antagonist, with LM3 denoting the peptide sequence p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2. It is utilized in the isotopic labeling of tumors for in vivo tracing, notably with 177Lu-DOTA-LM3 and 68Ga-DOTA-LM3. The derivative 68Ga-DOTA-LM3 exhibits promising biodistribution, high tumor uptake, efficient tumor retention, and minimal safety concerns, while 177Lu-DOTA-LM3 is applied in research on DOTATOC-negative liver metastases including pancreatic NET and extensive tumor thrombosis [1] [2].

NLRP3-IN-5, a compound disclosed in WO2016131098, is an inhibitor of NLRP3 inflammasome. It consists of the chemical structure N-((4-chloro-2,6-dimethylphenyl)carbamoyl)-4-(2-hydroxypropan-2-l)furan-2-sulfonamide.

H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.

Purpureaside C is a phenolic glycoside with significant proinflammatory, immunomodulating and antimicrobial effects.

DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist with the molecular structure p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2. It is effectively used in tracing tumors in vivo through isotopic labeling, examples being 177Lu-DOTA-LM3 TFA and 68Ga-DOTA-LM3 TFA. The 68Ga-labeled compound demonstrates favorable biodistribution, high tumor uptake, good tumor retention, and minimal safety concerns. Meanwhile, the 177Lu-labeled variant is utilized in research targeting DOTATOC-negative liver metastases such as pancreatic NET and extensive tumor thrombosis [1] [2].

N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.

D-Lysine lactam is a chiral building block.1,2It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists. 1.Kumar, A., Bhashkar, B., Bhavsar, J., et al.Catalytic reduction: Efficient synthesis of chiral key intermediate of besifloxacin hydrochlorideDer Pharma Chemica7(9)297-3000(2015) 2.Gerspacher, M., Lewis, C., Ball, H.A., et al.Stereoselective preparation of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide, a potent and orally active dual neurokinin NK(1)/NK(2) receptor antagonistJ. Med. Chem.46(16)3508-3513(2003)

DC-S239 (DC-S239) is a selective inhibitor of histone methyltransferase SETD7 (IC50 = 4.59 μM) with anticancer activity.