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Acetyl-CoA Carboxylase

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT).
Cat. No. Product name CAS No. Purity Chemical Structure
T5046 Haloxyfop 69806-34-4 100%
(±)-Haloxyfop is a herbicide.
T19982 Tralkoxydim 87820-88-0 98.22%
Tralkoxydim is an alkyl ketone herbicide. Tralkoxydim works as an ACCase inhibitor.
T1889 CP-640186 591778-68-6 98.67%
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal mus...
T7184 Firsocostat 1434635-54-7 99.01%
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
T3622 CP-640186 hydrochloride 591778-70-0 99.04%
CP-640186 HCl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM...
T9209 PF-05221304 1370448-25-1 99.19%
PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
T3510 Olumacostat Glasaretil 1261491-89-7 99.34%
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
T14991 CMS-121 1353224-53-9 99.48%
CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor with strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activitie...
TQ0243 ND-646 1434639-57-2 99.65%
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respective...
T3988 TOFA 54857-86-2 99.77%
TOFA is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
T7163 PF-05175157 1301214-47-0 99.78%
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, re...
Haloxyfop
T5046
(±)-Haloxyfop is a herbicide.
Tralkoxydim
T19982
Tralkoxydim is an alkyl ketone herbicide. Tralkoxydim works as an ACCase inhibitor.
CP-640186
T1889
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal mus...
Firsocostat
T7184
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
CP-640186 hydrochloride
T3622
CP-640186 HCl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM...
PF-05221304
T9209
PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
Olumacostat Glasaretil
T3510
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
CMS-121
T14991
CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor with strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activitie...
ND-646
TQ0243
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respective...
TOFA
T3988
TOFA is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
PF-05175157
T7163
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, re...