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Acetyl-CoA Carboxylase

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT).
Cat. No. Product name CAS No. Purity Chemical Structure
T7163 PF-05175157 1301214-47-0 98%
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, re...
T3988 TOFA 54857-86-2 98%
TOFA is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
TQ0243 ND-646 1434639-57-2 98%
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respective...
T14991 CMS-121 1353224-53-9 98%
CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor with strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activitie...
T9209 PF-05221304 1370448-25-1 98%
PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
T3622 CP-640186 hydrochloride 591778-70-0 98%
CP-640186 HCl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM...
T19982 Tralkoxydim 87820-88-0 98%
Tralkoxydim is an alkyl ketone herbicide. Tralkoxydim works as an ACCase inhibitor.
T7184 Firsocostat 1434635-54-7 98%
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
T5046 Haloxyfop 69806-34-4 98%
(±)-Haloxyfop is a herbicide.
T1889 CP-640186 591778-68-6 98%
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal mus...
T3510 Olumacostat Glasaretil 1261491-89-7 98%
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
PF-05175157
T7163
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, re...
TOFA
T3988
TOFA is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
ND-646
TQ0243
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respective...
CMS-121
T14991
CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor with strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activitie...
PF-05221304
T9209
PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
CP-640186 hydrochloride
T3622
CP-640186 HCl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM...
Tralkoxydim
T19982
Tralkoxydim is an alkyl ketone herbicide. Tralkoxydim works as an ACCase inhibitor.
Firsocostat
T7184
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
Haloxyfop
T5046
(±)-Haloxyfop is a herbicide.
CP-640186
T1889
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal mus...
Olumacostat Glasaretil
T3510
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.