Acetyl-CoA Carboxylase

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT).

Cat. No.	Product name	CAS No.	Purity
T5046	Haloxyfop	69806-34-4	100%
T5046	(±)-Haloxyfop is a herbicide.
T19982	Tralkoxydim	87820-88-0	98.22%
T19982	Tralkoxydim is an alkyl ketone herbicide. Tralkoxydim works as an ACCase inhibitor.
T1889	CP-640186	591778-68-6	98.67%
T1889	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal mus...
T7184	Firsocostat	1434635-54-7	99.01%
T7184	ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
T3622	CP-640186 hydrochloride	591778-70-0	99.04%
T3622	CP-640186 HCl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM...
T9209	PF-05221304	1370448-25-1	99.19%
T9209	PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
T3510	Olumacostat Glasaretil	1261491-89-7	99.34%
T3510	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
T14991	CMS-121	1353224-53-9	99.48%
T14991	CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor with strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activitie...
TQ0243	ND-646	1434639-57-2	99.65%
TQ0243	ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respective...
T3988	TOFA	54857-86-2	99.77%
T3988	TOFA is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
T7163	PF-05175157	1301214-47-0	99.78%
T7163	PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, re...