GTPase

GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP).

Cat No.	product name
T5142	NAV-2729	NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.
T2267	BQU57	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
T14897	CCG-63802	CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.
T21798L	Dynamin inhibitory peptide Acetate	Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.
T6634	RBC8	RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.
T14898	CCG-63808	CCG-63808 is a reversible inhibitor of the regulator of G-protein signaling (RGS) proteins.
T24706	RBC10	RBC10 is an inhibitor of the binding of Ral to its effector RALBP1 that acts by inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchor...
T21970	ML-097	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases
T25529	IMM-01	IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin fila...
T9200	Exo-1	Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate is a chemical compound.
T10705	CCG 203769	CCG 203769 is a selective inhibitor of G protein signaling (RGS4). It blocks the RGS4-Gαo protein-protein interaction in vitro (IC50: 17 nM).
TN4098	Gancaonin I	Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
T6434	CCG-50014	CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
T4022	QS11	QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling p...

Cat No.

product name

T5142

NAV-2729

NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.

T2267

BQU57

BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.

T14897

CCG-63802

CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.

T21798L

Dynamin inhibitory peptide Acetate

Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.

T6634

RBC8

RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.

T14898

CCG-63808

CCG-63808 is a reversible inhibitor of the regulator of G-protein signaling (RGS) proteins.

T24706

RBC10

RBC10 is an inhibitor of the binding of Ral to its effector RALBP1 that acts by inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchor...

T21970

ML-097

ML-097 (CID-2160985) is a pan activator of Ras-related GTPases

T25529

IMM-01

IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin fila...

T9200

Exo-1

Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate is a chemical compound.

T10705

CCG 203769

CCG 203769 is a selective inhibitor of G protein signaling (RGS4). It blocks the RGS4-Gαo protein-protein interaction in vitro (IC50: 17 nM).

TN4098

Gancaonin I

Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.

T6434

CCG-50014

CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.

T4022

QS11

QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling p...