GTPase

GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP).

Cat. No.	Product name	CAS No.	Purity
TN4098	Gancaonin I	126716-36-7	98%
TN4098	Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
T14898	CCG-63808	620113-73-7	98%
T14898	CCG-63808 is a reversible inhibitor of the regulator of G-protein signaling (RGS) proteins.
T14897	CCG-63802	620112-78-9	98%
T14897	CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.
T24706	RBC10	362503-73-9	98%
T24706	RBC10 is an inhibitor of the binding of Ral to its effector RALBP1 that acts by inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchor...
T21798L	Dynamin inhibitory peptide Acetate	T21798L	98%
T21798L	Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.
T21970	ML-097	743456-83-9	98%
T21970	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases
T4022	QS11	944328-88-5	98%
T4022	QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling p...
T6434	CCG-50014	883050-24-6	98%
T6434	CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
T2267	BQU57	1637739-82-2	98%
T2267	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
T25529	IMM-01	218795-74-5	98%
T25529	IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin fila...
T5142	NAV-2729	419547-11-8	98%
T5142	NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.
T10705	CCG 203769	410074-60-1	98%
T10705	CCG 203769 is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
T9200	Exo-1	461681-88-9	98%
T9200	Exo-1 is a synthetic compound that has been shown to affect the metabolism of various nutrients, as well as the regulation of various hormones. It has also been ...
T38387	Compound C108	15533-09-2	98%
T38387	Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and eso...
T6634	RBC8	361185-42-4	98%
T6634	RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.