GTPase

GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP).

Cat. No.	Product name	CAS No.	Purity
TN4098	Gancaonin I	126716-36-7	98%
TN4098	Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
T4022	QS11	944328-88-5	98%
T4022	QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling p...
T14897	CCG-63802	620112-78-9	98%
T14897	CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.
T14898	CCG-63808	620113-73-7	98%
T14898	CCG-63808 is a reversible inhibitor of the regulator of G-protein signaling (RGS) proteins.
T24706	RBC10	362503-73-9	98%
T24706	RBC10 is an inhibitor of the binding of Ral to its effector RALBP1 that acts by inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchor...
T25529	IMM-01	218795-74-5
T25529	IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin fila...
T21970	ML-097	743456-83-9
T21970	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases
T6434	CCG-50014	883050-24-6	98.69%
T6434	CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
T2267	BQU57	1637739-82-2	98.72%
T2267	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
T5142	NAV-2729	419547-11-8	98.83%
T5142	NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.
T10705	CCG 203769	410074-60-1	99.46%
T10705	CCG 203769 is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
T9200	Exo-1	461681-88-9	99.74%
T9200	Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate is a chemical compound.
T6634	RBC8	361185-42-4	99.86%
T6634	RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.
T21798L	Dynamin inhibitory peptide Acetate	T21798L
T21798L	Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.