Lipase

A carboxypeptidase is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of a protein or peptide. This is in contrast to an aminopeptidases, which cleave peptide bonds at the N-terminus of proteins. Humans, animals, bacteria and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation.

Cat. No.	Product name	CAS No.	Purity
T11939	MAGL-IN-1	2324160-91-8	98%
T11939	MAGL-IN-1 is a selective and potent monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 80 nM.
T16496	PF-06795071	2075629-81-9	98%
T16496	PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).
T1875	Atglistatin	1469924-27-3	98%
T1875	Atglistatin is a highly effective, specific and competitive ATGL inhibitor with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, and no toxicity when the...
T5353	ABX-1431	1446817-84-0	98%
T5353	ABX-1431 is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).
T2338	JZL195	1210004-12-8	98%
T2338	JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.
T2249	XEN445	1515856-92-4	98%
T2249	XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.
T9374	AA38-3	65815-76-1	98%
T9374	AA38-3 inhibites three SHs (ABHD6, ABHD11, and FAAH)
T2966	Beta-Sitosterol	83-46-5	98%
T2966	β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. β-Sitosterol, a m...
T3591	URB602	565460-15-3	98%
T3591	URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.
T27703	JZP-361	1680193-80-9	98%
T27703	JZP-361 is a specific MAGL inhibitor with IC50s of 46 nM, 7.24 μM, and 1.79 μM for human recombinant MAGL, human recombinant FAAH, and human hABHD6. JZP-361 disp...
T1846	Y-320	288250-47-5	98%
T1846	Y-320 is a new phenylpyrazoleanilide immunomodulator.
T15614	JJKK 048	1515855-97-6	98%
T15614	JJKK 048 is a potent and selective MAGL inhibitor.
T15632	JW 642	1416133-89-5	98%
T15632	JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, r...
T15635	JZP-430	1672691-74-5	98%
T15635	JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty...
T41160	Lalistat 2	1234569-09-5	98%
T41160	Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein...
T28165	NF-1819	1881244-28-5	98%
T28165	NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. NF-1819 alleviates symptoms in a MS model in vivo and exhi...
T5737	Euphol	514-47-6	98%
T5737	Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
T5815	MJN110	1438416-21-7	98%
T5815	Cravatt Reagent is a potent and selective MAGL inhibitor. Cravatt Reagent inhibits MAGL (IC50 = 9.1 nM). MJN110 Produces Opioid-Sparing Effects in a Mouse Neurop...
T6554	JZL 184	1101854-58-3	98%
T6554	JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.
T11199	Endothelial lipase inhibitor-1	1466427-02-0	98%
T11199	Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.