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Melanin-concentrating Hormone Receptor (MCHR)

Two Melanin-concentrating hormone receptors (MCHR) have recently been characterized: MCH-R1 and MCH-R2. These two receptors share approximately 38% homology. MCH-R1 is expressed in all mammals.MCH-R2 is only found in some primates and carnivores including dogs, ferrets and humans.
Cat. No. Product name CAS No. Purity Chemical Structure
T5406 SNAP 94847 487051-12-7 98%
SNAP-94847 is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake i...
T11966 MCHR1 antagonist 2 863115-70-2 98%
MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells. MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, w...
T8004 SNAP 94847 hydrochloride 1781934-47-1 100%
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
TP1953L PG 931 acetate 98.74%
PG-931 acetate is a potent agonist of melanocortin 4 (MC4) receptors.
TP1997L [Ala17]-MCH acetate TP1997L 98.92%
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled). [Ala17]-MCH acetate shows selectivity over MCHR...
TP1104L Melanin Concentrating Hormone, salmon acetate TP1104L 99.41%
Melanin Concentrating Hormone, salmon acetate is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.
TP1996 MCH(human, mouse, rat) 128315-56-0 99.55%
Potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 re...
TP1578L Neuropeptide EI, rat acetate TP1578L 95.55%
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
SNAP 94847
T5406
SNAP-94847 is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake i...
MCHR1 antagonist 2
T11966
MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells. MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, w...
SNAP 94847 hydrochloride
T8004
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
PG 931 acetate
TP1953L
PG-931 acetate is a potent agonist of melanocortin 4 (MC4) receptors.
[Ala17]-MCH acetate
TP1997L
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled). [Ala17]-MCH acetate shows selectivity over MCHR...
Melanin Concentrating Hormone, salmon acetate
TP1104L
Melanin Concentrating Hormone, salmon acetate is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.
MCH(human, mouse, rat)
TP1996
Potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 re...
Neuropeptide EI, rat acetate
TP1578L
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.