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PGE Synthase

Prostaglandin E synthase (or PGE synthase) is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E (PGE) from prostaglandin H2.The synthase generating PGE2 is a membrane-associated protein.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T79846 Friluglanstat 1422203-86-8 98%
Friluglanstat
Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].
T15757 Limaprost 74397-12-9 98%
Limaprost
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a pote...
T5843L (S)-Flurbiprofen 51543-39-6 99.88%
(S)-Flurbiprofen
Esflurbiprofen is an inhibitor of COX-1 and COX-2.
T0424 Bismuth Subsalicylate 14882-18-9 99.87%
Bismuth Subsalicylate
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion...
T5727 CAFESTOL 469-83-0 99.84%
CAFESTOL
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells....
T7948 HPGDS inhibitor 2 2101626-26-8 99.82%
HPGDS inhibitor 2
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.
T2681 HPGDS-IN-1 1234708-04-3 99.74%
hPGDS-IN-1
hPGDS-IN-1 is a hPGDS inhibitor.
T2S2335 Dehydroevodiamine 67909-49-3 99.12%
Dehydroevodiamine
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, ...
T4S0227 Sinensetin 2306-27-6 98.93%
Sinensetin
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin e...
T1866 AT-56 162640-98-4 98.43%
AT-56
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.
T0726 Benzydamine hydrochloride 132-69-4 98.42%
Benzydamine hydrochloride
Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.
T5681 ETHYL CAFFEATE 102-37-4 98%
ETHYL CAFFEATE
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely block...
T0159 Pranoprofen 52549-17-4 97.99%
Pranoprofen
Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.
T6687 Suprofen 40828-46-4 98%
Suprofen
Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthriti...
T0264 Zomepirac sodium salt 64092-48-4 98%
Zomepirac sodium salt
Zomepirac sodium salt (McN-2783-21-98) is a prostaglandin synthetase inhibitor.
T1804 HPGDS inhibitor 1 1033836-12-2 98%
HPGDS inhibitor 1
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM.
Friluglanstat
T79846
Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].
Limaprost
T15757
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a pote...
(S)-Flurbiprofen
T5843L
Esflurbiprofen is an inhibitor of COX-1 and COX-2.
Bismuth Subsalicylate
T0424
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion...
CAFESTOL
T5727
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells....
HPGDS inhibitor 2
T7948
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.
hPGDS-IN-1
T2681
hPGDS-IN-1 is a hPGDS inhibitor.
Dehydroevodiamine
T2S2335
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, ...
Sinensetin
T4S0227
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin e...
AT-56
T1866
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.
Benzydamine hydrochloride
T0726
Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.
ETHYL CAFFEATE
T5681
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely block...
Pranoprofen
T0159
Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.
Suprofen
T6687
Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthriti...
Zomepirac sodium salt
T0264
Zomepirac sodium salt (McN-2783-21-98) is a prostaglandin synthetase inhibitor.
HPGDS inhibitor 1
T1804
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM.
TargetMol