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c-Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
Cat. No. Product name CAS No. Purity Chemical Structure
T40419 IRES-C11 342416-30-2 98%
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ...
TN3708 Coronarin D 119188-37-3 98%
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
TN2177 Sanggenol L 329319-20-2 98%
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
TN4582 Moracin T 1146113-27-0 98%
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
T16839 SAJM589 2089-82-9 98%
sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
T11783 KSI-3716 1151813-61-4 98%
KSI-3716 is an inhibitor of c-Myc.
TN1354 Aaptamine 85547-22-4 98%
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
T10702 CBP/p300-IN-2 2158265-96-2 98%
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
TN4581 Moracin D 69120-07-6 98%
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
T60019 VPC-70063 13571-44-3 98%
VPC-70063 is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C downstrea...
T0617 Nicotinamide N-oxide 1986-81-8 98%
Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzy...
T3048 10058-F4 403811-55-2 98%
10058-F4 is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; in...
T2091 CPI0610 1380087-89-7 98%
CPI-0610 is an effective, specific, and cell-active BET bromodomain inhibitor CPI-0610 inhibits BRD4-BD1 (IC50: nM).
T9093 NY2267 886053-73-2 98%
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.
T4367 Mycro 3 944547-46-0 98%
Mycro 3 is potent and selective for c-Myc in whole cell assays.
T4252 ML327 1883510-31-3 98%
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
T10352 APTO-253 916151-99-0 98%
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates a...
T12132 MYCi361 2289690-31-7 98%
MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
TN1892 Lusianthridin 87530-30-1 98%
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-...
T9061 EN4 1197824-15-9 98%
EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional ...
IRES-C11
T40419
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ...
Coronarin D
TN3708
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
Sanggenol L
TN2177
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
Moracin T
TN4582
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
sAJM589
T16839
sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
KSI-3716
T11783
KSI-3716 is an inhibitor of c-Myc.
Aaptamine
TN1354
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
CBP/p300-IN-2
T10702
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
Moracin D
TN4581
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
VPC-70063
T60019
VPC-70063 is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C downstrea...
Nicotinamide N-oxide
T0617
Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzy...
10058-F4
T3048
10058-F4 is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; in...
CPI0610
T2091
CPI-0610 is an effective, specific, and cell-active BET bromodomain inhibitor CPI-0610 inhibits BRD4-BD1 (IC50: nM).
NY2267
T9093
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.
Mycro 3
T4367
Mycro 3 is potent and selective for c-Myc in whole cell assays.
ML327
T4252
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
APTO-253
T10352
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates a...
MYCi361
T12132
MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
Lusianthridin
TN1892
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-...
EN4
T9061
EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional ...
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