Home Tools
Log in
Cart

c-Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
Cat No. product name
TN1892 Lusianthridin Lusianthridin 是来自石斛Dendrobium venustum的天然产物。 Lusianthridin 在无毒浓度下表现出抗迁移特性。 Lusianthridin 通过抑制 Src-STAT3 信号传导增强 c-Myc 降解。
T9628 10074-A4 10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from th...
T10352 APTO-253 APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates a...
T9033 BTYNB MDK6620 is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces a...
T3048 10058-F4 10058-F4 is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; in...
T12134 MYCMI-6 MYCMI-6 is a potent and selective inhibitor of endogenous MYC:MAX protein interactions,reduces proliferation and induces massive apoptosis in tumor tissue from a...
T4367 Mycro 3 Mycro 3 is potent and selective for c-Myc in whole cell assays.
T0617 Nicotinamide N-oxide Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzy...
T4252 ML327 ML327 is a blocker of MYC which can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
T3686 10074-G5 10074-G5 is an inhibitor of c-Myc-Max dimerization.
TN2177 Sanggenol L Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
TN1354 Aaptamine Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
T9093 NY2267 NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.
T9061 EN4 EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional ...
T10702 CBP/p300-IN-2 CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
T11783 KSI-3716 KSI-3716 is an inhibitor of c-Myc.
T12132 MYCi361 MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
TN3708 Coronarin D Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
TN4582 Moracin T Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
TN4581 Moracin D Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
T16839 SAJM589 sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
T15665 KJ Pyr 9 KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).
Lusianthridin
TN1892
Lusianthridin 是来自石斛Dendrobium venustum的天然产物。 Lusianthridin 在无毒浓度下表现出抗迁移特性。 Lusianthridin 通过抑制 Src-STA...
10074-A4
T9628
10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct featur...
APTO-253
T10352
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates a...
BTYNB
T9033
MDK6620 is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and redu...
10058-F4
T3048
10058-F4 is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; in...
MYCMI-6
T12134
MYCMI-6 is a potent and selective inhibitor of endogenous MYC:MAX protein interactions,reduces proliferation and induces massive apoptosis in tumor tissue from...
Mycro 3
T4367
Mycro 3 is potent and selective for c-Myc in whole cell assays.
Nicotinamide N-oxide
T0617
Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzy...
ML327
T4252
ML327 is a blocker of MYC which can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
10074-G5
T3686
10074-G5 is an inhibitor of c-Myc-Max dimerization.
Sanggenol L
TN2177
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
Aaptamine
TN1354
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
NY2267
T9093
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.
EN4
T9061
EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional ...
CBP/p300-IN-2
T10702
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
KSI-3716
T11783
KSI-3716 is an inhibitor of c-Myc.
MYCi361
T12132
MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
Coronarin D
TN3708
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
Moracin T
TN4582
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
Moracin D
TN4581
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
sAJM589
T16839
sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
KJ Pyr 9
T15665
KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).