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Tithonia

Tagitinin C
T12458059979-56-5
Tagitinin C is a sesquiterpene compound derived from Tithonia diversifolia, an inducer of ferroptosis with anti-cancer activity. It induces ferroptosis through the PERK-Nrf2-HO-1 signaling pathway.
  • $298
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Tagitinin A
TN509159979-61-2
Tagitinin A is a naturally occurring sesquiterpene lactone compound that acts as a dual agonist of peroxisome proliferator-activated receptor α γ (PPARα PPARγ) and exerts antihyperglycemic and antihyperlipidemic effects in diabetes research.Tagitinin A is able to bind directly to the ligand-binding domain of PPARγ (IC50=55 μM), and also stimulates the PPAR Tagitinin A can directly bind to the PPARγ ligand binding domain (IC50=55 μM) and also stimulate the PPARα-dependent activation of the SULT2A1 gene promoter. As a phytotoxin, Tagitinin A significantly inhibited the growth of wheat germ sheath.
  • $1,698
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1-Acetyltagitinin A
TN252560547-63-9
1-Acetyltagitinin A is a natural product of Tithonia, Asteraceae. The catalog number is TN2525 and the CAS number is 60547-63-9. 1-Acetyltagitinin A can be used as a reference standard.
  • $550
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3-O-Methyltirotundin
TN29751021945-29-8
3-O-Methyltirotundin is a natural product of Tithonia, Asteraceae. The catalog number is TN2975 and the CAS number is 1021945-29-8. 3-O-Methyltirotundin can be used as a reference standard.
  • $660
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Tagitinin F
TN509259979-57-6
Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes.
  • $550
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Tirotundin
TN514956377-67-4
Tirotundin is a PPARα γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activation of NF-kappa B, thereby, the synthesis of inflammatory mediators such as cytokines and chemo
  • $550
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6,7-Dihydroneridienone A
TN314572959-46-7
6,7-Dihydroneridienone A exhibits notable leishmanicidal activity.
  • $550
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